云南大学化学科学与工程学院
史勇（博士，研究员，硕士生导师）
专业：有机化学（有机合成方向）
可主讲课程：有机化学、高等有机、有机合成反应、天然产物合成等
电子邮件：yshi@ynu.edu.cn
ORCID: 0000-0002-7887-3050
受教育及工作经历
1999-2003年，南京大学化学化工学院，获理学学士
2004-2009年，中国科学院上海有机化学研究所，获理学博士学位（导师：田伟生 研究员；方向有机合成）
2009-2018年，中国科学院上海有机化学研究所天然产物有机合成化学重点实验室工作，先后任助理研究员和副研究员
2018年12月至今，云南大学化学科学与工程学院工作
研究兴趣和领域
天然产物（甾体和萜类为主）和药物的合成及高效合成方法研究。
论文和著作
[1] Gao, R.; Shi, Y.*; Tian, W.-S.* An improved synthesis of pennogenin. Tetrahedron 2019, 75, (12), 1717–1721.
[2] Shi, Y.*; Xiao, Q.; Lan, Q.; Wang, D.-H.; Jia, L.-Q.; Tang, X.-H.; Zhou, T.; Li, M.; Tian, W.-S.* A synthesis of cephalostatin 1. Tetrahedron 2019, 75, (12), 1722–1738.
[3] Deng, J.-C.; Wu, J.-J.; Tian, H.-L.; Bao, J.-J.; Shi, Y.; Tian, W.-S.*; Gui, J.-H.* Alkynes from furans: A general fragmentation method applied to the synthesis of the proposed structure of aglatomin B. Angew. Chem. Int. Ed. 2018, 57, (14), 3617-3621.
[4] Wu, J.-J.; Shi, Y.*; Tian, W.-S.* Synthesis of the aglycon of aspafiliosides E and F via a spiroketal-forming cascade. Tetrahedron Lett. 2017, 58, (10), 923-925.
[5] Shi, Y.*; Jiang, X.-L.; Tian, W.-S.* Synthesis of 12,12′-azo-13,13′-diepi-Ritterazine N. J. Org. Chem. 2017, 82, (1), 269-275.
[6] Jiang, X.-L.; Shi, Y.*; Tian, W.-S.* Synthesis of 18-demethoxy analogues of the aglycon of saundersiosides A and B based on a cascade process. Asian J. Org. Chem. 2017, 6, (8), 1024-1027.
[7] Jiang, X.-L.; Shi, Y.*; Tian, W.-S.* Constructing 24(23→22)-abeo-cholestane from tigogenin in a 20(22→23)-abeo-way via a PhI(OAc)2-mediated Favorskii rearrangement. J. Org. Chem. 2017, 82, (8), 4402-4406.
[8] Hou, L.-L.; Shi, Y.*; Zhang, Z.-D.; Wu, J.-J.; Yang, Q.-X.; Tian, W.-S.* Divergent synthesis of solanidine and 22-epi-solanidine. J. Org. Chem. 2017, 82, (14), 7463-7469.
[9] Zhou, T.; Feng, F.; Shi, Y.*; Tian, W.-S.* Synthesis toward and stereochemical assignment of clathsterol: exploring diverse strategies to polyoxygenated sterols. Org. Lett. 2016, 18, (9), 2308-2311.
[10] Zhang, Z.-D.; Shi, Y.*; Wu, J.-J.; Lin, J.-R.; Tian, W.-S.* Synthesis of demissidine and solanidine. Org. Lett. 2016, 18, (12), 3038-3040.
[11] Xin, P.; Yan, J.; Li, B.; Fang, S.; Fan, J.; Tian, H.; Shi, Y.; Tian, W.; Yan, C.; Chu, J.* A Comprehensive and effective mass spectrometry-based screening strategy for discovery and identification of new brassinosteroids from rice tissues. Frontiers in Plant Science 2016, 7, (1786), 1786.
[12] Wu, J.-J.; Shi, Y.*; Tian, W.-S.* Synthesis of the aglycon of aspafiliosides E and F based on cascade reactions. Chem. Commun. 2016, 52, (9), 1942-1944.
[13] Wang, Y.; Chen, F.-E.; Shi, Y.*; Tian, W.-S.* Multigram scale, chiron-based synthesis of sacubitril. Tetrahedron Lett. 2016, 57, (52), 5928-5930.
[14] Wu, J.-J.; Shi, Y.*; Tian, W.-S.* Facile synthesis of solasodine based on a mild halogenation-ring opening reaction of spiroketals in steroidal sapogenins. Tetrahedron Lett. 2015, 56, (10), 1215-1217.
[15] Wu, J.-J.; Gao, R.; Shi, Y.*; Tian, W.-S.* Direct amination of EF spiroketal in steroidal sapogenins: an efficient synthetic strategy and method for related alkaloids. Tetrahedron Lett. 2015, 56, (47), 6639-6642.
[16] Tian, W.; Shi, Y. Resource Chemistry. Chin. J. Chem. 2015, 33, (6), 619-620. (Guest co-editor, six papers in this special issue)
[17] Hao, X.; Wu, J.; Tian, H.; Shi, Y.*; Lin, J.; Tian, W.-S.* A short synthesis of clionamine D. Chin. J. Chem. 2015, 33, (11), 1235-1238. (Cover paper)
[18] Cheng, S.-L.; Jiang, X.-L.; Shi, Y.*; Tian, W.-S.* Concise synthesis of the core structures of saundersiosides. Org. Lett. 2015, 17, (10), 2346-2349.
[19] Zhang, X.-F.; Wu, J.-J.; Shi, Y.*; Lin, J.-R.; Tian, W.-S.* Formal synthesis of osladin based on an activation relay process. Tetrahedron Lett. 2014, 55, (33), 4639-4642.
[20] Wang, S.-S.; Shi, Y.*; Tian, W.-S.* Highly Efficient and Scalable Synthesis of Clionamine D. Org. Lett. 2014, 16, (8), 2177-2179.
[21] Shi, Y.; Jia, L.-Q.; Xiao, Q.; Lan, Q.; Tang, X.-H.; Wang, D.-H.; Li, M.; Ji, Y.; Zhou, T.; Tian, W.-S.* A practical synthesis of cephalostatin 1. Chem. Asian J. 2011, 6, (3), 786-790.
[22] Huang, C.-X.; Shi, Y.; Lin, J.-R.; Jin, R.-H.; Tian, W.-S.* Grignard reagent induced tandem semipinacol rearrangement/ketone addition reaction of 20S-hydroxy-5α-pregnane-16(17)-epoxide. Tetrahedron Lett. 2011, 52, (32), 4123-4125.
综述和图书章节
[23] 有机合成中的副反应——芳香族分子取代反应，佛罗伦西奥萨拉戈萨多沃德 著，田伟生、史勇 译，华东理工大学出版社：上海，2017
[24] 田伟生、史勇，第十八章 先锋甾亭1，天然产物全合成荟萃——抗生素及其他，吴毓林 主编，科学出版社：北京，2014
[25] 史勇、田伟生，第十九章 考替甾亭A，天然产物全合成荟萃——抗生素及其他，吴毓林 主编，科学出版社：北京，2014
[26] 黄培强; 赵刚; 刘国生; 岳建民; 胡金波; 史勇; 田伟生 有机化学进展(2011--2012). 化学通报 2014, 77, (7), 586-622.
[27] 田伟生、史勇，资源化学研究进展，化学进展，2010, 22 (4), 537—556.
[27] 史勇、田伟生，新型甾体血管新生抑制剂Cortistatin的结构、生物活性与合成，有机化学, 2010, 30 (4), 515—527.
科研项目和专利
1、具有抗病毒活性的双裂孕甾醇类天然产物集体全合成策略研究，国家自然科学基金面上项目(21572248)，2016/01-2019/12，主持
2、田伟生、史勇、王莎莎、汪昀，一种16S-甲基-20S-羟基孕甾化合物：合成方法及其用途，2013.11.13，中国专利，201110353934.X
3、田伟生、史勇、黄春希、汪昀，一种16-甲基-17-羟基孕甾-3,20-二酮化合物及其合成方法，2012.11.07，中国专利，201110110319.6
