云南大学化学科学与工程学院
杨亚滨（博士，教授，博士生导师）
专业：分析化学
主讲课程：
主讲专业必修课《药物化学》、《有机化学实验》和全校选修课《药物与疾病》。
团队：分离分析团队
电话：0871-65033719
电子信箱：ybyang@ynu.edu.cn
受教育经历及工作经历：
1996、2003年先后获云南大学化学系理学学士学位、中科院昆明植物研究所理学博士学位；
2003至今 云南大学化学科学与工程学院工作。
教学：
主讲专业必修课《药物化学》、全校选修课《药物与疾病》及国家级精品课程《有机化学实验》。
研究领域和兴趣：
研究领域：天然产物化学。
主要兴趣为：特殊生境微生物中新颖活性化合物的发现和云南特色中药资源的活性成分研究。
论文、专著：
学术论文
1. Li-Jiao Shi, Ya-Mei Wu, Xue-Qiong Yang, Ting-Ting Xu, Shuang Yang, Xue-Yin Wang, Ya-Bin Yang（通讯作者）, Zhong-Tao Ding. The cocultured Nigrospora oryzae and Collectotrichum gloeosporioides, Irpex lacteus, and the plant host Dendrobium officinale bidirectionally regulate the production of phytotoxins by anti-phytopathogenic metabolites. Journal of Natural Products, 2020, 83, 1374−1382.
2. Ya-Mei Wu, Qing-Yan Zhou, Xue-Qiong Yang, Yu-Jie Luo, Jing-Jing Qian, Shi-Xi Liu, Ya-Bin Yang（通讯作者）, Zhong-Tao Ding. Induction of antiphytopathogenic metabolite and squalene production and phytotoxin elimination by adjustment of the mode of fermentation in cocultures of phytopathogenic Nigrospora oryzae and Irpex lacteus. Journal of Agriculture and Food Chemistry, 2019, 67, 11877−11882.
3. Bang-Yan Wang, Xue-Qiong Yang, Ming Hu, Li-Jiao Shi, Hai-Yue Yin, Ya-Mei Wu, Ya-Bin Yang（通讯作者）, Hao Zhou, Zhong-Tao Ding. Biotransformation of natural polyacetylene in red ginseng by Chaetomium globosum. Journal of Ginseng Research, https://doi.org/10.1016/j.jgr.2019.06.007.
4. Bang-Yan Wang, Ya-Bin Yang(并列第一） , Xue-Qiong Yang, Chen-Hao Zhu, Shuang Yang, Ting-Ting Xu, Xue-Yin Wang, Ning-Hua Tan, Hao Zhou, Zhong-Tao Ding. Inducing secondary metabolite production from Daldinia eschscholzii JC-15 by red ginseng medium. Natural Product Research, https://doi.org/10.1080/14786419.2019.1610751
5. Bang-Yan Wang, Chen-Hao Zhu, Xue-Qiong Yang, Ming Hu, Ting-Ting Xu, Xue-Yin Wang, Shuang Yang, Ya-Bin Yang（通讯作者）, Zhong-Tao Ding. Inducing intermediates in biotransformation of natural polyacetylene and a novel spiro-γ-lactone from red ginseng by solid co-culture of two gut Chaetomium globosum and the potential bioactivity modification by oxidative metabolism. Molecules, 2020, 25, 1216.
6. Ming Hu, Xue-Qiong Yang, Qing-Yan Zhou, Shu-Quan Li, Bang-Yan Wang, Bao-Hui Ruan, Ya-Bin Yang(通讯作者）, Zhuo-Xi Zhang, Hao Zhou, Zhong-Tao Ding. Benzopyran derivatives from endophytic Daldinia eschscholzii JC-15 in Dendrobium chrysotoxum and their bioactivities. Natural Product Research, 2019, 33, 1431–1435.
7. Qing-Yan Zhou, Xue-Qiong Yang, Zhuo-Xi Zhang, Bang-Yan Wang, Ming Hu, Ya-Bin Yang（通讯作者）, Hao Zhou, Zhong-Tao Ding. New azaphilones and tremulane sesquiterpene from endophytic Nigrospora oryzae cocultured with Irpex lacteus. Fitoterapia, 2018, 13, 26-30.
8. Na Luo, Ya-Bin Yang(并列第一）, Xue-Qiong Yang, Cui-Ping Miao, Yi-Qing Li, Li-Hua Xu, Zhong-Tao Ding，Li-Xing Zhao. The streptazolin- and obscurolide-type metabolites from soil-derived Streptomyces alboniger YIM20533 and the mechanism of influence of g-butyrolactone on the growth of Streptomyces by their non-enzymatic reactionbiosynthesis. RSC Advances, 2018, 8, 35042–35049.
9. Zhuo-Xi Zhang, Xue-Qiong Yang, Qing-Yan Zhou, Bang-Yan Wang, Ming Hu, Ya-Bin Yang (通讯作者）, Hao Zhou, Zhong-Tao Ding. New azaphilones from Nigrospora oryzae co-cultured with Beauveria bassiana. Molecules, 2018, 23, 1816.
10. Bao-Hui Ruan, Shu-Quan Li, Xue-Qiong Yang, Ya-Bin Yang (通讯作者）, Ya-Mei Wu, Li-Jiao Shi, Hai-Yue Yin, Hao Zhou, Zhong-Tao Ding. New bisabosquals from Stachybotrys sp. PH30583 elicited on solid media. Molecules, 2018, 23, 1577.
11. Ming Hu, Xue-Qiong Yang, Chuen-Ping Wan, Bang-Yan Wang, Hai-Yue Yin, Li-Jiao Shi, Ya-Mei Wu, Ya-Bin Yang (通讯作者）, Hao Zhou, Zhong-Tao Ding. Potential antihyperlipidemic polyketones from endophytic Diaporthe sp. JC-J7 in Dendrobium nobile. RSC Advances, 2018, 8, 41810–41817.
12. Qiang Wang, Ya-Bin Yang (并列第一）, Xue-Qiong Yang, Cui-Ping Miao, Yi-Qing Li, Shi-Xi Liu, Na Luo, Zhong-Tao Ding, Li-Xing Zhao. Lovastatin analogues and other metabolites from soil-derived Aspergillus terreus YIM PH30711. Phytochemistry, 2018,145, 146-152.
13. Bao-Hui Ruan, Ze-Fen Yu, Xue-Qiong Yang, Ya-Bin Yang （通讯作者）, Ming Hu, Zhuo-Xi Zhang, Qing-Yan Zhou, Hao Zhou， Zhong-Tao Ding. New bioactive compounds from aquatic endophyte Chaetomium globosum. Natural Product Research, 2018, 32, 1050-1055.
14. Qiang Wang, Xue-Qiong Yang, Cui-Ping Miao, Li-Hua Xu, Zhong-Tao Ding, Ya-Bin Yang (通讯作者）, Li-Xing Zhao. A new pair of pentaketide diastereoisomers from Aspergillus melleus. YIM PHI001. Records of Natural Products. 2018, 12, 216-221.
15. Wei Li, Ya-Bin Yang (并列第一), Xue-Qiong Yang, Hui-Ding Xie, Zhi-Hui Shao, Hao Zhou, Cui-Ping Miao, Li-Xing Zhao, Zhong-Tao Ding. Novel isochroman dimers from Stachybotrys sp. PH30583: Fermentation, isolation, structural elucidation and biological activities. Planta Medica, 2017, 83, 654–660.
16. Wei Li, Xue-Qiong Yang, Ya-Bin Yang（通讯作者）, Li-Xing Zhao, Qing-Yan Zhou, Zhuo-Xi Zhang, Hao Zhou, Ming Hu, Bao-Hui Ruan and Zhong-Tao Ding. A novel steroid derivative and a new steroidal saponin from endophytic fungus Xylaria sp. Natural Product Communications, 2017, 12, 901-904.
17. Ju-cheng Zhang, Guang-Yi Chen, Xiao-Zhan Li, Ming Hu, Bang-Yan Wang, Bao-Hui Ruan, Hao Zhou, Li-Xing Zhao, Jun Zhou, Zhong-Tao Ding, Ya-Bin Yang （通讯作者）. Phytotoxic, antibacterial, and antioxidant activities of mycotoxins and other metabolites from Trichoderma sp.. Natural Product Research, 2017, 31, 2745–2752.
18. Xiao-Zhan Li, Bao-Hui Ruan, Ya-Bin Yang （通讯作者）, Xue-Qiong Yang, Guang-Yi Chen, Ming Hu, Bang-Yan Wang, Hao Zhou, Zhong-Tao Ding. Metabolites from Penicillium sp. associated with Paris polyphylla. Natural Product Communications, 2017,12,87-88.
19. Ju-Cheng Zhang, Ya-Bin Yang (并列第一）, Guang-Yi Chen, Xiao-Zhan Li, Ming Hu, Bang-Yan Wang, Bao-Hui Ruan, Hao Zhou, Li-Xing Zhao, Zhong-Tao Ding. 8′-epimer of herbicidin F and its congeners from Streptomyces sp. YIM 66142. The Journal of Antibiotics, 2017, 70, 313–316.
科研项目、成果和专利：
l 主持承担4项国家自然科学基金项目：基于多样性导向的混合培养策略下铁皮石斛内生菌中活性新颖化合物及其相互作用的化学机制研究81960640 (2020-2023), 两种云南特色中药化学成分诱导其同源内生菌代谢活性新颖化合物的研究81660582（2017-2020），五种云南民族药用植物内生链霉菌的新奇结构化合物及其生物活性研究81360480 (2014-2017)，4种云南特境放线菌抗肿瘤新活性成分的发现81060263 (2011-2013)；
l 主持承担1项云南省应用基础面上项目（已结题）：云南药用花卉植物活性成分研究（2008-2010）.
l 主持1项云南大学中青年骨干教师培养计划（已结题）和1项教育部重点实验室开放基金（已结题）。
奖励、荣誉和学术兼职：
2019年获红云园丁奖， 2014年获云南大学第十八届伍达观教育基金优秀教师奖，云南大学东陆学者
