Wen Chen
 |
Associate Professor |
Office: Chemistry Building 6F |
Tel.: 86-(0)871-6531119/13116201168 |
Email: chenwenchem@163.com |
Address: Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University), Ministry of Education, Yunnan University, 2 North Cuihu Road, 650091 Kunming, P.R.China |
Brief Introduction
Associate Professor, Yunnan University (2017 - )
Assistant Professor, Yunnan University (2015 – 2017)
Ph.D., Yunnan University (2011.9 - 2014.12)
M.S., Yunnan Minzu University (2008.9 - 2011.7)
B.S., Yunnan Minzu University (2004.9 - 2008.7)
Research Interests
Total synthesis of natural products and pharmaceuticals
Foundation and Projects
1. Natural Science Foundation of China 21762047 (2018-2021), responsible;
2. Applied basic research projects of Yunnan Province 2017FB10 (2016 - 2019), responsible;
3. Applied basic research projects of Yunnan Province 2016FD007 (2016 - 2019), responsible;
4. Donglu young talent teacher of Yunnan University (2017-2020) , responsible；
5. Opening Foundation of Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education (2017KF01), responsible.
Representative Publications
1. Wen Chen, Xiao-Dong Yang, Wen-Yun Tan, Xiang-Yang Zhang, Xia-Li Liao, and Hongbin Zhang, Total Synthesis of (-)-Vindorosine, Angewandte Chemie International Edition, 2017, 56, 12327-12331.
2. Wen Chen, Jian Ren, Minshou Wang, Lingjing Dang, Xianfu Shen, Xiaodong Yang Hongbin Zhang, Iodine mediated deprotection of N-tert-butanesulfinyl amines: a functional group compatible method, Chemical Communications, 2014, 50, 6259-6262.
3. Wen Chen, Hongbin Zhang*, Asymmetric construction of all-carbon quaternary stereocenters in the total synthesis of natural products, Science China Chemistry, 2016, 59, 1065-1078.
4. Wen Chen, Xiao-Dong Yang, Yan Li, Li-Juan Yang, Xue-Quan Wang, Gao-Lan Zhang, Hong-Bin Zhang, Design, synthesis and cytotoxic activities of novel hybrid compounds between dihydrobenzofuran and imidazole, Organic & Biomolecular Chemistry, 2011, 9, 4250-4255.
5. Guijun Li, Xiaoliang Xu, Hongchang Tian, Xiaotong Liu, Wen Chen*, Xiaodong Yanga and Hongbin Zhang*, Asymmetric synthesis of δ-amino acid derivatives via diastereoselective vinylogous Mannich reactions between N-tert-butanesulfinyl imines and dioxinone-derived lithium dienolate, RSC Advances, 2017, 7, 50822-50828.
6. Chao-Bo Zhang, Yang Liu, Zheng-Fen Liu, Sheng-Zu Duan, Min-Yan Li, Wen Chen*, Yan Li, Hong-Bin Zhang, Xiao-Dong Yang*, Synthesis and cytotoxic activity of novel tetrahydrobenzodifuran–imidazolium salt derivatives, Bioorganic & Medicinal Chemistry Letters, 2017, 27, 1808-1814.
