Jingbo Chen Ph. D., Doctoral supervisor
Professor, academic and technical leader of Yunnan Province
1986-1990 B.S. Shenyang Pharmaceutical University, Shenyang
1990-1993 M.S. candidate, Shenyang Pharmaceutical University, Shenyang
2004-2004 Visiting Researcher Scholar, Graduate School and Faculty of Pharmaceutical Sciences, Kyoto University
2004-2009 Ph. D. candidate, Yunnan University, Kunming
1993-2000 Research Assistant/Research Associate, Center for drug R&D, Yunnan University
2000-2003 Research Associate, School of Pharmacy, Yunnan University
2003-2013 Associate professor, Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education of China, School of Chemical Science and Technology, Yunnan University
2013-2014 Post-Doc./ Visiting Researcher Scholar，Institute of Microbial Chemistry (IMC), Tokyo
2013-present Professor, Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education of China, Yunnan University
Research Interests
Design, Synthesis and Structure-activity Relationship of Bioactive Molecules
Step-Economical Organic Synthetic methods
Synthesis of Complex Natural Products
Representative Publications
1. Short, enantioselective, gram-scale synthesis of (-)-zephyranthine, Yuxiang Zhao;Yanren Zhu; Guolan Ma; Qi Wei; Shaoxiong Yang; Xiaoyu Zeng; Hongbin Zhang*; Jingbo Chen*, Chemical Science, 2021, 12(27): 9452-9457.
2. The effect of carbonyl on the isomerization of a galanthan ring system and total synthesis of (+/-)-beta-lycorane, Liang, Leilei; Li, Ji; Shen, Baochun; Zhang, Yili; Liu, Jianping; Chen, Jingbo*; Liu, Dandan*, Organic and Biomolecular Chemistry, 2021, 19(12): 2767-2772.
3. Highly regioselective ring-opening of epoxides with amines: a metal- and solvent-free protocol for the synthesis of beta-amino alcohols, Li, Dong; Wang, Jing; Yu, Shibo; Ye, Silei; Zou, Wenjie; Zhang, Hongbin*; Chen, Jingbo*. Chemical Communications, 2020, 56(15): 2256-2259.
4. TRIM67 promotes NF-kappa B pathway and cell apoptosis in GA-13315-treated lung cancer cells. Liu, Rui; Chen, Yajuan; Shou, Tao; Hu, Jing; Chen, Jingbo*; Qing, Chen*. Molecular Medicine Reports, 2019, 20(3): 2936-2944.
5. Jingbo Chen, Jingchao Chen, Yan Xie, Hongbin Zhang*, EnantioselectiveTotal Synthesis of (–)-Stenine, Angew. Chem. Int. Ed., 2012, 51, 1024–1027.
6. Jingchao Chen, Yan Xie, Jingbo Chen*, Hongbin Zhang*，Asymmetric total synthesis of (−)-stenine，Asymmetric total synthesis of (−)-stenine, Tetrahedron, 2015, 71, 3747–3755.
7. Rui Yang#, Jing-Bo Chen#, Chuan-Fan Xiao, Zhi-Cheng Liu, Zhan-Yong Gao,Sheng-Jiao Yan, Ji-Hong Zhang,* Hong-Bin Zhang,*Jun Lin,*Inclusion complex of GA-13316 with b-cyclodextrin: Preparation,characterization, molecular modeling, and in vitro evaluation, Carbohydrate Polymers, 2014, 111, 655–662.
8. Jingbo Chen*, Zhuxian Sun, Yanli Zhang, Jingchao Chen, Panghui Li, XianghuiZeng,Benlin Yin, Yan Xie, Chen Qing,*, Hongbin Zhang*, Synthesis and anticancer activities of C-13 etheralgibberelline derivatives，Chinese Journal of Organic Chemistry, 2014, 34, 788–796.
9. Jingbo Chen, Jingchao Chen, Yan Xie, Nana Liu, Dandan Liu, Hongbin Zhang*,Research Progress on the Synthesis of Stenine，Chinese Journal of Organic Chemistry, 2013, 33, 1186–1194.
Rui Yang#, Jing-Bo Chen#, Xiao-Yang Dai, Rong Huang, Chuan-Fan Xiao, Zhan-Yong Gao,Bo Yang, Li-Juan Yang, Sheng-Jiao Yan, Hong-Bin Zhang*, Chen Qing*, Jun Lin*, Inclusioncomplexof GA-13315withcyclodextrins:Preparation,characterization, inclusion mode and properties, Carbohydrate Polymers, 2012, 89, 89-97.
