Chengfeng Xia, Ph. D.
Professor of Chemistry
Email:xiacf@ynu.edu.cn
Key Laboratory of Medicinal Chemistry for Natural Resource
Yunnan University
No.2 North Cuihu Road, Kunming, P. R. China
1992 – 1997B.S., Peking University, Beijing
1997 – 2002Ph.D., Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
2004-2009Postdoctoral fellow, The Ohio State University
2009-2015Professor, Kunming Institute of Botany, Chinese Academy of Sciences
2015-present Professor, Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University
Research Interests
Current research interest includes the discovery of new methods via single electron transfer process, development of new strategies and tactics, and total synthesis of natural products.
Representative Publications
1. Shao, L.-D.; Su, J.; Ye, B.; Liu, J.-X.; Zuo, Z.-L.; Li, Y.; Wang, Y.-Y.*;Xia, C.*; Zhao, Q.-S.* “Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors”Journal of Medicinal Chemistry,2017,60, 9053-9066.
2. Li, D.; Wu, T.; Liang, K.;Xia, C.*“Curtius-like Rearrangement of an Iron-Nitrenoid Complex and Application in Biomimetic Synthesis of Bisindolylmethanes”Organic Letters,2016,18, 2228−2231.
3. Liang, K.; Yang, J.; Tong, X.; Shang, W.; Pan, Z.;Xia, C.* “Biomimetic Synthesis of Moschamine-Related Indole Alkaloids via Iron-Catalyzed Selectively Oxidative Radical Coupling”Organic Letters,2016,18, 1474−1477.
4. Pan, Z.; Qin, X.-J.; Liu, Y.-P.; Wu, T.; Luo, X.-D.*;Xia, C.* “Alstoscholarisines H−J, Indole Alkaloids from Alstoniascholaris: Structural Evaluation and Bioinspired Synthesis of Alstoscholarisine H”Organic Letters,2016,18, 654-657.
5. Liang, K.; Deng, X.; Tong, X.; Li, D.; Ding, M.; Zhou, A.;Xia, C.* “Copper-Mediatd Dimerization to Access 3a,3a´-Bispyrrolidinoindoline: Diastereoselective Synthesis of (+)-WIN 64821 and (-)-Ditryptophenaline”Organic Letters2015,17, 206-209.
6. Xu, J.; Shao, L. D.; Li, D.; Deng, X.; Liu, Y. C.; Zhao, Q. S.*;Xia, C.* “Construction of Tetracyclic 3‑Spirooxindole through Cross-Dehydrogenation of Pyridinium: Applications in Facile Synthesis of (±)-Corynoxine and (±)-Corynoxine B”Journal of the American Chemistry Society2014,136, 17962-17965.