Lin Jinyan
Assistant Professor, Department of Occupational and Environmental Health, Xi'an Jiaotong University
Research fields (directions)
Application of pathological microenvironment-responsive nanodrug delivery systems in the treatment of common chronic diseases such as tumors and osteoarthritis.
Education and Experience
2024/08-till now, Department of Occupational and Environmental Health, Xi'an Jiaotong University, Assistant Professor.
2019/09-2023/09，Mengchao Hepatobiliary Hospital of Fujian Medical University, Postdoctor
2014/09-2019/06, College of Materials, Xiamen University, Ph.D.
2010/09-2013/06, College of Materials, Xiamen University, M.S.
Projects
[1] National Natural Science Foundation of China (Grant No. 8200071676), Oxygen-Independent Radical Nanogenerator for Cascade-Responsive Photothermal-Photodynamic-Chemodynamic Synergistic Therapy of Hypoxic Tumors. 2020.09-2022.12.PI.
[2] China Postdoctoral Science Foundation Grant (Grant No. 2020M671928), Near-Infrared Light and Redox Cascade-Responsive Radical Nanoinitiator for Photothermal Synergistic Photodynamic and Chemodynamic Therapy of Hypoxic Tumors. 2020.07-2023.06. PI.
Selected publications
[1] Lin Jin-Yan#, He Yue-Yang#, Li Yang*, Chen Jian-Wu*, Liu Xiao-Long*. Oxygen-Evolving Low-Dose X-Ray Radiotherapy-Radiodynamic Therapy Synergized with NO Gas Therapy by Cerium-based Rare-Earth Metal-Porphyrin Framework, Small. 2024, 2310957.
[2] Lin Jin-Yan#, Huang Cai-Lin#, Wang Pei-Yuan#, He Yue-Yang, Luo Qiang, Liu Xiao-Long*, Li Yang*. Tumor-Microenvironment-Responsive Cerium-Enriched Copper Nanozyme with O2 Supply and Oxidative Stress Amplification for In Situ Disulfiram Chemotherapy and Chemodynamic Therapy Intensification. Advanced Healthcare Materials. 2023, 2303955.
[3] Lin Jin-Yan#, Li Yang#*, Wang Pei-Yuan, Wu Ming, Zhu Fu-Kai, Zhang Yun, Hou Zhen-Qing, Liu Jing-Feng, Liu Xiao-Long*. Natural Killer Cell Membrane-Cloaked Virus-Mimicking Nanogenerator with NIR-Triggered Shape Reversal and •C/•OH Storm for Synergistic Thermodynamic-Chemodynamic Therapy, Advanced Science. 2021, 9, 2103498-2103514.
[4] Li Yang#, Lin Jin-Yan#, Wang Pei-Yuan, Zhu Fu-Kai, Wu Ming, Luo Qiang, Zhang Yun, Liu Xiao-Long*. Tumor Microenvironment-Responsive Yolk-Shell NaCl@Virus-Inspired Tetrasulfide-Organosilica for Ion-Interference Therapy via Osmolarity Surge and Oxidative Stress Amplification, ACS Nano. 2022, 16, 7380-7397. (Co-first author)
[5] Li Yang#, Lin Jin-Yan#, Cai Zhi-Xiong, Wang Pei-Yuan, Luo Qiang, Zhang, Yun, Hou Zhen-Qing*, Liu Jing-Feng*, Liu Xiao-Long*. Tumor Microenvironment-Activated Self-Recognizing Nanodrug through Directly Tailored Assembly of Small-Molecules for Targeted Synergistic Chemotherapy, Journal of Controlled Release. 2020, 321, 222-235. (Co-first author)
[6] Li Yang#, Lin Jin-Yan#, Wang Pei-Yuan, Luo Qiang, Lin Hui-Rong, Zhang Yun, Hou Zhen-Qing, Liu Jing-Feng*, Liu Xiao-Long*. Tumor Microenvironment Responsive Shape-Reversal Self-Targeting Virus-Inspired Nanodrug for Imaging-Guided Near-Infrared-II Photothermal Chemotherapy, ACS Nano. 2019, 13, 12912-12928. (Co-first author)
Contact information
Email: linjinyan@xjtu.edu.cn
Address: 76 Yanta West Road, Yanta District, Xi’an, Shaanxi, China 710061
