Aggregation-Induced Emission : Applications
[Book Description]
Edited by the academic who first discovered this important phenomenon, Aggregation-Induced Emission is the first book to cover the applications of Aggregation-Induced Emission. This groundbreaking text explores the high-tech applications of AIE materials in optoelectronic devices, chemical sensors, and biological probes. A valuable resource for scientists, physicists, and biological chemists, topics covered include: AIE materials for LEDs and lasers; mechanochromic AIE materials; new chemo- and biosensors based on AIE fluorophores; AIE dye-encapsulated nanoparticles for optical bioimaging; and chiral recognition and enantiomeric excess determination based on AIE.
[Table of Contents]
List of Contributors xi
Preface xiii
1 AIE or AIEE Materials for 1 (42)
Electroluminescence Applications
Chiao-Wen Lin
Chin-Ti Chen
1.1 Introduction 1 (1)
1.2 EL Background, EL Efficiency, Color 2 (5)
Chromaticity, and Fabrication Issues of
OLEDs
1.3 AIE or AIEE Silole Derivatives for 7 (3)
OLEDs
1.4 AIE or AIEE Maleimide and Pyrrole 10 (4)
Derivatives for OLEDs
1.5 AIE or AIEE Cyano-Substituted 14 (3)
Stilbenoid and Distyrylbenzene
Derivatives for OLEDs
1.6 AIE or AIEE Triarylamine Derivatives 17 (1)
for OLEDs
1.7 AIE or AIEE Triphenylethene and 17 (14)
Tetraphenylethene Derivatives for OLEDs
1.8 White OLEDs Containing AIE or AIEE 31 (5)
Materials
1.9 Perspectives 36 (7)
References 37 (6)
2 Crystallization-Induced Phosphorescence 43 (18)
for Purely Organic Phosphors at Room
Temperature and Liquid Crystals with
Aggregation-Induced Emission Characteristics
Wang Zhang Yuan
Yongming Zhang
Ben Zhong Tang
2.1 Crystallization-Induced 43 (9)
Phosphorescence for Purely Organic
Phosphors at Room Temperature
2.1.1 Introduction 43 (1)
2.1.2 Molecular luminogens with 44 (8)
crystallization-induced phosphorescence
at room temperature
2.2 Liquid Crystals with 52 (5)
Aggregation-Induced Emission
Characteristics
2.2.1 Luminescent liquid crystals 52 (1)
2.2.2 Aggregation-induced emission 53 (4)
strategy towards high-efficiency
luminescent liquid crystals
2.3 Conclusions and Perspectives 57 (4)
References 58 (3)
3 Mechanochromic Aggregation-Induced 61 (26)
Emission Materials
Zhenguo Chi
Jiarui Xu
3.1 Introduction 61 (1)
3.2 Mechanochromic Non-AIE Compounds 62 (2)
3.3 Mechanochromic AIE Compounds 64 (18)
3.4 Conclusion 82 (5)
References 83 (4)
4 Chiral Recognition and Enantiomeric 87 (20)
Excess Determination Based on
Aggregation-Induced Emission
Yan-Song Zheng
4.1 Introduction to Chiral Recognition 87 (1)
4.2 Chiral Recognition and Enantiomeric 88 (3)
Excess Determination of Chiral Amines
4.3 Chiral Recognition and Enantiomeric 91 (10)
Excess Determination of Chiral Acids
4.3.1 Enantiomeric excess determination 91 (7)
of chiral acids using chiral AIE amines
4.3.2 Enantiomeric excess determination 98 (3)
of chiral acids using a chiral receptor
in the presence of an AIE compound
4.4 Mechanism of Chiral Recognition Based 101 (3)
on AIE
4.4.1 Mechanism of chiral recognition 102 (1)
by a chiral AIE monoamine
4.4.2 Mechanism of chiral recognition 102 (2)
by a chiral AIE diamine
4.5 Prospects for Chiral Recognition 104 (3)
Based on AIE
References 105 (2)
5 AIE Materials Towards Efficient 107 (24)
Circularly Polarized Luminescence, Organic
Lasing, and Superamplified Detection of
Explosives
Jianzhao Liu
Jacky W.Y. Lam
Ben Zhong Tang
5.1 Introduction 107 (1)
5.2 AIE Materials with Efficient 107 (11)
Circularly Polarized Luminescence and
Large Dissymmetry Factor
5.2.1 Aggregation-induced circular 108 (2)
dichroism
5.2.2 AIE, fluorescence decay dynamics 110 (3)
and theoretical understanding
5.2.3 Aggregation-induced circularly 113 (2)
polarized luminescence
5.2.4 Supramolecular assembly and 115 (3)
structural modeling
5.3 AIE Materials for Organic Lasing 118 (3)
5.3.1 Fabrication of nano-structures 118 (1)
5.3.2 Lasing performances 119 (2)
5.4 AIE Materials for Superamplified 121 (6)
Detection of Explosives
5.4.1 Hyperbranched polymer-based sensor 122 (5)
5.4.2 Mesoporous material-based sensor 127 (1)
5.5 Conclusion 127 (4)
References 128 (3)
6 Aggregation-Induced Emission and 131 (26)
Applications of Aryl-Substituted Pyrrole
Derivatives
Bin Tong
Yuping Dong
6.1 Introduction 131 (1)
6.2 Luminescence Properties of 132 (4)
Triphenylpyrrole Derivatives in the
Aggregated State
6.3 Applications 136 (11)
6.4 Aggregation-Induced Emission of 147 (3)
Pentaphenylpyrrole
6.5 AIEE Mechanism of Pentaphenylpyrrole 150 (2)
6.6 Conclusion 152 (5)
References 152 (5)
7 Biogenic Amine Sensing with 157 (8)
Aggregation-Induced Emission-Active
Tetraphenylethenes
Takanobu Sanji
Masato Tanaka
7.1 Introduction 157 (1)
7.1.1 Biogenic amines 157 (1)
7.1.2 Sensing methods for biogenic 157 (1)
amines
7.2 Fluorimetric Sensing of Biogenic 158 (5)
Amines with AIE-Active TPEs
7.2.1 Design for fluorimetric sensing 158 (1)
of biogenic amines
7.2.2 Sensing studies and statistical 158 (4)
analysis
7.2.3 Determination of histamine 162 (1)
concentration
7.2.4 Fluorimetric sensing of melamine 163 (1)
with AIE-active TPEs
7.3 Summary and Outlook 163 (2)
References 164 (1)
8 New Chemo-/Biosensors with Silole and 165 (24)
Tetraphenylethene Molecules Based on the
Aggregation and Deaggregation Mechanism
Ming Wang
Guanxin Zhang
Deqing Zhang
8.1 Introduction 165 (1)
8.2 Cation and Anion Sensors 166 (3)
8.3 Fluorimetric Biosensors for 169 (4)
Biomacromolecules
8.4 Fluorimetric Assays for Enzymes 173 (7)
8.5 Fluorimetric Detection of 180 (3)
Physiologically Important Small Molecules
8.6 Miscellaneous Sensors 183 (2)
8.7 Conclusion and Outlook 185 (4)
References 185 (4)
9 Carbohydrate-Functionalized AIE-Active 189 (20)
Molecules as Luminescent Probes for
Biosensing
Qi Chen
Bao-Hang Han
9.1 Introduction 189 (1)
9.2 Carbohydrate-Bearing AIE-Active 190 (5)
Molecules
9.2.1 Carbohydrate-bearing siloles 191 (1)
9.2.2 Carbohydrate-bearing phosphole 192 (1)
oxides
9.2.3 Carbohydrate-bearing 193 (2)
tetraphenylethenes
9.3 Luminescent Probes for Lectins 195 (4)
9.4 Luminescent Probes for Enzymes 199 (4)
9.5 Luminescent Probes for Viruses and 203 (2)
Toxins
9.6 Conclusion 205 (4)
Acknowledgments 205 (1)
References 205 (4)
10 Aggregation-Induced Emission Dyes for In 209 (30)
Vivo Functional Bioimaging
Jim Qian
Dan Wang
Sailing He
10.1 Introduction 209 (1)
10.2 AIE Dyes for Macro In Vivo 210 (13)
Functional Bioimaging
10.2.1 AIE dye-encapsulated 210 (1)
phospholipid-PEG nanomicelles
10.2.2 AIE dye-encapsulated 210 (6)
nanomicelles for SLN mapping of mice
10.2.3 AIE dye-encapsulated 216 (5)
nanomicelles for tumor targeting of mice
10.2.4 Other types of AIE-nanoparticles 221 (2)
for in vivo functional bioimaging
10.3 Multiphoton-Induced Fluorescence 223 (9)
from AIE Dyes and Applications in In Vivo
Functional Microscopic Imaging
10.3.1 Two- and three-photon-induced 223 (4)
fluorescence of AIE dyes
10.3.2 AIE dye-encapsulated 227 (3)
nanomicelles for two-photon blood
vessel imaging of live mice
10.3.3 AIE dye-encapsulated 230 (2)
nanomicelles for two-photon brain
imaging of live mice
10.4 Summary and Perspectives 232 (7)
Acknowledgments 234 (1)
References 234 (5)
11 Specific Light-Up Bioprobes with 239 (20)
Aggregation-Induced Emission
Characteristics for Protein Sensing
Jing Liang
Haibin Shi
Ben Zhong Tang
Bin Liu
11.1 Introduction 239 (1)
11.2 In Vitro Detection of Integrin 240 (5)
αβ3 Using a TPS-Based Probe
11.2.1 Detection mechanisms 241 (1)
11.2.2 Synthesis and characterization 241 (2)
of the TPS-2cRGD probe
11.2.3 Detection of integrin in 243 (1)
solutions
11.2.4 In vitro sensing of integrin in 244 (1)
cancer cells
11.3 Real-Time Monitoring of Cell 245 (6)
Apoptosis and Drug Screening with a
TPE-Based Probe
11.3.1 Design principles 245 (1)
11.3.2 Synthesis and characterization 246 (1)
of Ac-DEVEK-TPE probe
11.3.3 Detection of caspase and kinetic 247 (1)
study of caspase activities in solutions
11.3.4 Imaging of cell apoptosis and 248 (3)
screening of apoptosis-inducing agents
11.4 In Vivo Monitoring of Cell Apoptosis 251 (4)
and Drug Screening with PyTPE-Based Probe
11.4.1 Working principles 251 (1)
11.4.2 Synthesis and characterization 252 (1)
of DEVD-PyTPE probe
11.4.3 Monitoring of caspase activities 253 (1)
in solutions
11.4.4 In vitro and in vivo imaging of 253 (2)
cell apoptosis
11.5 Conclusion 255 (4)
Acknowledgments 255 (1)
References 256 (3)
12 Applications of Aggregation-Induced 259 (16)
Emission Materials in Biotechnology
Yuning Hong
Jacky W. Y. Lam
Ben Zhong Tang
12.1 Introduction 259 (1)
12.2 AIE Materials for Nucleic Acid 260 (3)
Studies
12.2.1 Quantitation and gel 260 (2)
visualization of DNA and RNA
12.2.2 Specific probing of G-quadruplex 262 (1)
DNA formation
12.3 AIE Materials for Protein Studies 263 (6)
12.3.1 Quantitation and PAGE staining 263 (3)
of proteins
12.3.2 Fluorescence immunoassay by AIE 266 (1)
materials
12.3.3 Monitoring of the 266 (1)
unfolding/refolding process of human
serum albumin
12.3.4 Monitoring and inhibition of 267 (2)
amyloid fibrillation of insulin
12.4 AIE Materials for Live Cell Imaging 269 (2)
12.4.1 AIE bioprobes for long-term cell 269 (1)
tracking
12.4.2 AIE nanoparticles for cell 269 (2)
staining
12.5 Conclusion 271 (4)
References 272 (3)
Index 275
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