Yugen Zhu, Ph.D
Associate Professor
Key Laboratory of Medicinal Chemistry for Natural Resource
Yunnan University
No.2 North Cuihu Road, Kunming, P. R. China
Email: yugenzhu@ynu.edu.cn
Brief Introduction
Associate Professor, Yunnan University (2019.5 - present)
Postdoc, University of Georgia (2016.12–2019.2)
Postdoc, University of Colorado at Boulder (2015.3 – 2016.11)
Ph.D., Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (2009.7 – 2014.9)
M.S., China Pharmaceutical University (2005.7 – 2009.9)
Research Interests
1) Synthesis of complex oligosaccharide and glycoconjugate of biological importance,
2) Development of new methodology for carbohydrate synthesis,
3) Development of carbohydrate-based drugs and vaccines
Representative Publications
1. Zhu, Y.; Yu, B.＊ Characterization of the Isochromen-4-yl-gold(I) Intermediate in the Gold(I)-Catalyzed Glycosidation of Glycosyl ortho-Alkynylbenzoates and Enhancement of the Catalytic Efficiency Thereof Angew. Chem. Int. Ed. 2011, 50, 8329-8332.
2. Zhu, Y.; Yu, B.＊ Highly Stereoselective β-Mannopyranosylation via the 1-a-Glycosyloxy-isochromenylium-4-gold(I) Intermediates Chem. Eur. J. 2015, 21, 8771-8780. (Inside Cover).
3. Zhu, Y.†; Shen, Z. †; Li, W.; Yu, B.* Stereoselective synthesis of β-rhamnopyranosides via gold(I)-catalyzed glycosylation with 2-alkynyl- 4-nitro-benzoate donors Org. Biomol. Chem. 2016, 14, 1536-1539.
4. Zhu, Y.†; He, W.†; Wang, W.; Pitsch, C.; Wang, X.; Wang, X. * Enantioselective Tandem Cyclization of Alkyne-Tethered Indoles Using Cooperative Silver(I)/Chiral Phosphoric Acid Catalysis Angew. Chem. Int. Ed. 2017, 56, 12206-12209.
5. Zhu, Y. †; Cleaver, L†.; Wang, W.; Podoll, J.; Walls, S.; Jolly, A.; Wang, X.* Tetracyclic indolines as a novel class of b-lactam-selective resistance-modifying agent for MRSA Eur. J. Med. Chem. 2017, 125, 130-142.
