Professor Doctor Advisor |
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Office: Chemistry Building |
Tel.: 86-(0)871-65031633 |
Email: linjun@ynu.edu.cn |
Address: School of Chemical Science and Technology, Yunnan University 2 North Cuihu Road, 650091 Kunming, P.R.China |
Brief Introduction
(Associate/Assistant) Professor, Yunnan University (1993 - present)
Visiting Scholar, University of Arizona (1996.8–1998.1)
Senior Visiting Scholar, University of Oxford (2002.8 – 2003.8)
Senior Research Scientist, MIT (2016.1–2016.4)
Ph.D., Kunming Institute of Botany, Chinese Academy of Sciences (1995 - 1998)
M.S., Yunnan University (1990 - 1993)
Research Interests
Organic synthesis, Drug synthesis and Organic synthesis methodology
Main interests: (1) Study on the design and synthesis of active pharmaceutical naturalproduct-like heterocyclic compounds; (2) Small molecule chiral catalytic reaction and asymmetric synthesis; (3) Supramolecular chemistry of complex natural products; (4) Extraction, synthesis and activity of pesticide active compounds with high efficiency and low toxicity.
Foundation and Projects
1. Study on the synthesis of novel 1,2,4-oxadiazole heterocyclic compounds and their biological mechanism based on nano probe, NSFC 81760621, (2018.1-2021.12), responsible
2. Design, Synthesis and Antitumor Activity Study of NovelAnti-angiogenic Tyrosine Kinase Inhibitors,NSFCU1202221, (2013.1-2016.12), responsible
3. Diversity oriented synthesis of polycyclic indole heterocyclic compoundsand their antitumoractivities,NSFC 21262042, (2013.1-2016.12), responsible 4. Study on the synthesis and antitumor activity of a variety of natural product-like heterocyclic compounds, project of “YunlingScholar”, (2015.1-2019.12), responsible |
Representative Publications
Kaixiu Luo, Shuai Mao, Kun He, Xianglin Yu, Junhong Pan, Jun Lin*, Zhihui Shao*, and Yi Jin*, Highly Regioselective Synthesis of Multisubstituted Pyrroles via Ag-Catalyzed [4+1C]insert Cascade, ACS Catalysis, 2020, 10, 3733−3740.
Lingbin Kong, Rong Huang, Haodan He, Yunxiang Fan, Jun Lin* and Sheng-Jiao Yan*, Multi-component solvent-free cascade reaction of 2-cyanoacetamides: regioselective synthesis of pyridin-2-ones bearing quaternary centers, Green Chemistry, 2020, 22, 256-264.
Peng Chen,† Kaixiu Luo,† Xianglin Yu, Xu Yuan, Xiaoyu Liu, Jun Lin* and Yi Jin*, Cu-Catalyzed Direct Amination of Cyclic Amides via C-OH Bond Activation Using DMF, Organic Letters, 2020, 22, 6547-6551.
Cong-Hai Zhang, Rong Huang, Xia Qing, Jun Lin,* Sheng-Jiao Yan*. Cascade Reaction of Isatins with Nitro-substituted Enamines: Highly Selectively Synthesis of Functionalized (Z)-3-(1-(Arylamino)-2-oxoarylidene)indolin-2-ones. Chemical Communications, 2020, 56, 3488-3491.
Xuan-Xuan Du, Quan-Xing Zi, Yu-Meng Wu, Yi Jin,* Jun Lin*, and Sheng-Jiao Yan*, An environmentally benign multi-component reaction: Regioselective synthesis of fluorinated 2-aminopyridines using diverse properties of nitro group, Green Chemistry, 2019, 21, 1505-1516.
Kaixiu Luo, Yongqiang Zhao, Jiawei Zhang, Jia He, Rong Huang, Shengjiao Yan*, Jun Lin* and Yi Jin*, Enantioselective Epoxypyrrolidines via a Tandem Cycloaddition/Autoxidation in Air and Mechanistic Studies, Organic Letters, 2019, 21, 423-427.
Patents
[1] Yi Jin, Jun Lin, Li-Ping-Shi,Preparation and application of Multi halogen substituted phenyl cyanide-quinazolone compounds, CN ZL201310242148.1, 2015-10-14.
[2] Yi Jin, Jun Lin, Liang Xi, Sheng-Jiao Yan, Ling Hu, Juan Fan, Preparation and application of a class of Quinazoline aryl ureas, CN ZL201210430235.5, 2015-11-20.
APPOINTMENTS & POSITIONS
Member of Chinese Chemical Society, China, 1993-present
