Bing Xu:Self-Assembled Biomaterials
Posted on:2024-06-12 hits:

卢嘉锡讲座

报告题目:Self-Assembled Biomaterials

报告时间:2024-06-21 10:00

报告人: Prof. Bing Xu(徐兵)

Brandeis University

报告地点:卢嘉锡楼202报告厅

转播地点:翔安校区源材料大楼3号楼会议室5,漳州校区生化主楼307教室


报告摘要:

In this talk, we will discuss the use of self-assembly to generate biomaterials for various applications. Particularly, we will show three examples. The first case focuses on cell spheroid creation by transcytotic intercellular gelation, a study that couples transcytosis and morphological transformation of peptide assemblies for regenerative medicine and tissue engineering. The second example highlights the cryo-EM structures of nanofibers formed through self-assembly of intrinsically disordered peptides (IDPs), particularly aromatic motif-capped phosphorylated short IDPs. The last case centers on the self-assembly of unnatural peptides, which deplete endogenous cholesterol from cell membranes. We intend to demonstrate the power of molecular design in self-assembled biomaterials.


报告人简介:

Bing Xu1987 年于南京大学化学系取得本科学位,1990 年于南京大学化学系获得硕士学位,1996 年获得宾夕法尼亚大学博士学位(导师:Timothy Swager 教授),1997-2000年在美国哈佛大学(合作导师:George Whitesides教授)从事博士后研究。2000 8 月,以独立课题组长加盟香港科技大学,2006 年被聘为副教授,2008 8 月被聘为教授。2008 9 月进入美国布兰迪斯大 (Brandeis University),目前为布兰迪斯大学化学系教授。已发表 260 余篇论文,被引用超过 28000 次,h-index 85。曾获多个奖项,如 Human Frontier Science Program AwardDistinguished Lectureship AwardAward of Chemical Society of Japan。他在金属凝胶、多功能磁性纳米颗粒、超分子水凝胶,以及酶驱动自组装体系等领域做出开创性贡献。他是“111”创新引智计划基地的海外专家。


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