（1）单个活细胞的光寻址电化学成像。对传统光寻址电位传感成像技术进行改进，基于半导体-电解液界面发展了新型光电化学成像系统，最终实现了单个活细胞光寻址电化学成像，可检测单细胞表面电荷分布，适用于成骨细胞，小鼠神经细胞，人间充质干细胞等多种细胞类型，并用于单细胞动态过程免标记成像监测。（Anal. Chem., 2019, 91, 5896-5903;  Anal. Chem. 2023, 95(23): 8898-8905；Anal. Chem. 2024, 96(50): 19988–19995）

（2）光寻址方波伏安法及其在生物传感与成像中的应用。提出了一种新型光寻址方波伏安法，采用恒定激光照射场效应结构半导体芯片，激发产生原位光生载流子，通过方波电压脉冲调制光生载流子的定向迁移和扩散过程，检测得到原位光电流，对其光电流的信号机制给出了完整的解释。将光寻址方波伏安法用于离子传感、酶促反应检测和电化学阻抗成像。（ ACS Sens. 2021, 6(4): 1636-1642）

2024

(1) Yao Meng^#; Yaqiong Wang^#; Sen Wang; Mingrui Jiang; De-Wen Zhang*; Jian Zhuang*; Jian Wang*, Photocurrent Polarity-Switchable Imaging of Single Living Cells by Light-Addressable Electrochemical Sensor. Analytical Chemistry 2024, 96(50): 19988–19995.  https://doi.org/10.1021/acs.analchem.4c04565  (IF = 6.7)

(2) Qiaoyu Yang; Jiaming Liao; Luyao Feng; Sen Wang; Zhibin Zhao; Jian Wang*; Yazhong Bu*; Jian Zhuang; De-Wen Zhang*, One-step construction of multiplexed enzymatic biosensors using light-addressable electrochemistry on a single silicon photoelectrode. Biosensors and Bioelectronics 2024, 253, 116194. https://doi.org/10.1016/j.bios.2024.116194  (IF = 10.7)

2023

(1) Fangming Chen^#, Qian Guo^#, Qiaoyu Yang, Yao Meng, Mingrui Jiang, Jian Wang*, De-Wen Zhang*. Label-Free Imaging of Cell Apoptosis by a Light-Addressable Electrochemical Sensor. Analytical Chemistry 2023, 95(23): 8898-8905.   https://pubs.acs.org/doi/10.1021/acs.analchem.3c00566  (IF = 6.7)

(2) Mingrui Jiang, Fangming Chen, Yao Meng, Qiaoyu Yang, Jian Wang, De-Wen Zhang*, Yaqiong Wang*. Carbonized polydopamine layer-protected silicon substrates for light-addressable electrochemical sensing and imaging. Talanta 2023, 254: 124124. https://doi.org/10.1016/j.talanta.2022.124124  (IF = 5.6)

(3) Jian Wang, Fangming Chen, Qiaoyu Yang, Yao Meng, Mingrui Jiang, Yaqiong Wang, De-Wen Zhang*, Liping Du*. Light-addressable electrochemical immunoassay for multiplexed detection of antigen. Sensors and Actuators B: Chemical 2023, 374: 132821. https://doi.org/10.1016/j.snb.2022.132821 (IF = 8.0)

2022

(1) Fangming Chen, Qiaoyu Yang, MingRui Jiang, Yao Meng, De-Wen Zhang*, Jian Wang*. Visualization of electrochemical reactions on microelectrodes using light-addressable potentiometric sensor imaging. Analytica Chimica Acta 2022, 1224: 340237. https://doi.org/10.1016/j.aca.2022.340237 (IF = 6.2)

(2) Yao Meng, Fangming Chen, Chunsheng Wu, Steffi Krause, Jian Wang*, De-Wen Zhang*. Light-Addressable Electrochemical Sensors toward Spatially Resolved Biosensing and Imaging Applications. ACS Sensors 2022, 7(7): 1791-1807.  https://doi.org/10.1021/acssensors.2c00940 (IF = 8.9)

2021 

(1) Yao Meng, Fangming Chen, Mingrui Jiang, Qin Guo, Yaqiong Wang, Jian Wang*, De-Wen Zhang*. A Homogeneous Label-Free Electrochemical microRNA Biosensor Coupling With G-Triplex/Methylene Blue Complex and λ-Exonuclease-Assisted Recycling Amplification. Frontiers in Chemistry 2021, 9(975). (IF = 5.545)

(2) Jian Wang, Fangming Chen, Qin Guo, Yao Meng, Mingrui Jiang, Chunsheng Wu, Jian Zhuang, De-Wen Zhang*. Light-Addressable Square Wave Voltammetry (LASWV) Based on a Field-Effect Structure for Electrochemical Sensing and Imaging. ACS Sensors 2021, 6(4): 1636-1642.  (IF = 9.618)

(3) Fangming Chen, Xingchuang Fu, Yao Meng, Mingrui Jiang, Jian Wang*, Ying-Lin Zhou*, De-Wen Zhang*. A novel miniaturized homogeneous label-free electrochemical biosensing platform combining integrated microelectrode and functional nucleic acids. Analytica Chimica Acta 2021, 1158: 338415.  (IF = 6.911)

(4) Bo Zhou, Anirban Das*, Muchun Zhong, Qian Guo, De-Wen Zhang, Karin A. Hing, Ana Jorge Sobrido, Maria-Magdalena Titirici, Steffi Krause*. Photoelectrochemical imaging system with high spatiotemporal resolution for visualizing dynamic cellular responses. Biosensors and Bioelectronics 2021, 180: 113121-113121. (IF = 12.545)

(5) Yun-Chong Li, Bo Jiao*, Yi-Jun Zhang, Jian Wang*, Wei Ren, De-Wen Zhang, Xun Hou, Zhao-Xin Wu*. Bipolar Light-Addressable Potentiometric Sensor Based on Fullerene Photosensitive Layer. Advanced Materials Technologies 2021, 6(8): 2001221. (IF = 8.856)

2020 

(1) Jian Wang^#, Yulan Tian^#, Fangming Chen, Wei Chen, Liping Du, Zhiyuan He, Chunsheng Wu*, De-Wen Zhang*. Scanning Electrochemical Photometric Sensors for Label-Free Single-Cell Imaging and Quantitative Absorption Analysis. Analytical Chemistry 2020, 92(14): 9739-9744. (IF = 6.986)

(2) Ying Tu, Candice Kyle, Hui Luo, De-Wen Zhang, Anirban Das, Joe Briscoe, Steve Dunn, Maria-Magdalena Titirici, Steffi Krause*. Ammonia Gas Sensor Response of a Vertical Zinc Oxide Nanorod-Gold Junction Diode at Room Temperature. ACS Sensors 2020, 5(11): 3568-3575. (IF = 7.711)

2019 

(1) Jian Wang, Zhao Yang, Wei Chen, Liping Du, Bo Jiao, Steffi Krause, Ping Wang, Qiuping Wei, De-Wen Zhang^*, Chunsheng Wu^*. Modulated light-activated electrochemistry at silicon functionalized with metal-organic frameworks towards addressable DNA chips. Biosensors and Bioelectronics 2019, 146: 111750.  (IF = 10.257)

(2) Jian Wang, Shu Kong, Fangming Chen, Wei Chen, Liping Du, Wen Cai, Liquan Huang, Chunsheng Wu^*, De-Wen Zhang^*. A bioelectronic taste sensor based on bioengineered Escherichia coli cells combined with ITO-constructed electrochemical sensors. Analytica Chimica Acta 2019, 1079: 73-78. (IF = 5.977)

(3) Fan Wu, Bo Zhou, Jian Wang, Muchun Zhong, Anirban Das, Michael Watkinson, Karin Hing, De-Wen Zhang^*, Steffi Krause^*. Photoelectrochemical Imaging System for the Mapping of Cell Surface Charges. Analytical Chemistry 2019, 91(9): 5896-5903. (IF = 6.785)

(4)  Norlaily Ahmad, Burcu Colak, Martin John Gibbs, De-Wen Zhang, Julien E. Gautrot, Michael Watkinson, C. Remzi Becer, Steffi Krause*. Peptide Cross-Linked Poly(2-oxazoline) as a Sensor Material for the Detection of Proteases with a Quartz Crystal Microbalance. Biomacromolecules 2019, 20(7): 2506-2514. (IF = 6.092)

 Before 2018

(1) Ying Tu, Norlaily Ahmad, Joe Briscoe, De-Wen Zhang^*, Steffi Krause^*, Light-Addressable Potentiometric Sensors Using ZnO Nanorods as the Sensor Substrate for Bioanalytical Applications. Analytical Chemistry, 2018, 90, 8708-8715. 

(2) De-Wen Zhang, Nikolaos Papaioannou, Naomi Michelle David, Hui Luo, Hui Gao, Liviu Cristian Tanase, Thibault Degousée, Paolo Samorì, Andrei Sapelkin, Oliver Fenwick, Maria-Magdalena Titirici^*, Steffi Krause^*, Photoelectrochemical Response of Carbon Dots (Cds) Derived from Chitosan and Their Use in Electrochemical Imaging. Materials Horizons 2018, 5, 423-428. 

(3) De-Wen Zhang, Fan Wu, Steffi Krause^*, LAPS and SPIM Imaging Using Ito-Coated Glass as the Substrate Material. Analytical Chemistry, 2017, 89, 8129-8133. 

(4)  Fan Wu, Inmaculada Campos, De-Wen Zhang^*, Steffi Krause^*, Biological Imaging Using Light-Addressable Potentiometric Sensors and Scanning Photo-Induced Impedance Microscopy. Proceedings of the Royal Society. A, Mathematical, physical, and engineering sciences, 2017, 473, 20170130.

(5) De-Wen Zhang, Fan Wu, Jian Wang, Michael Watkinson, Steffi Krause^*, Image Detection of Yeast Saccharomyces Cerevisiae by Light-Addressable Potentiometric Sensors (LAPS). Electrochemistry Communications, 2016, 72, 41-45. 

(6) Ting Cao, Ji Nie, Liang-Yuan Cai, Xiao-Hui Zhang, De-Wen Zhang*, Ying-Lin Zhou*, Xin-Xiang Zhang*, A Cupric Ion Triggered DNA Diode Based on a Tandem Linkage-Cleavage Reaction. Chemical Communications, 2016, 52, 12490-12493. 

(7) De-Wen Zhang, Ji Nie, Fang-Ting Zhang, Li Xu, Ying-Lin Zhou*, Xin-Xiang Zhang*, Novel Homogeneous Label-Free Electrochemical Aptasensor Based on Functional DNA Hairpin for Target Detection. Analytical Chemistry, 2013, 85, 9378-9382.

(8) De-Wen Zhang, Jing-Xin Liu, Ji Nie, Ying-Lin Zhou*, Xin-Xiang Zhang*, Micropipet Tip-Based Miniaturized Electrochemical Device Combined with Ultramicroelectrode and Its Application in Immobilization-Free Enzyme Biosensor. Analytical Chemistry, 2013, 85, 2032-2036.

(9) De-Wen Zhang, Cui-Jin Sun, Fang-Ting Zhang, Li Xu, Ying-Lin Zhou*, Xin-Xiang Zhang*, An Electrochemical Aptasensor Based on Enzyme Linked Aptamer Assay. Biosensors and Bioelectronics, 2012, 31, 363-368. 

(10) De-Wen Zhang, Fang-Ting Zhang, Yi-Ran Cui, Qin-Pei Deng, Steffi Krause, Ying-Lin Zhou*, Xin-Xiang Zhang*, A Label-Free Aptasensor for the Sensitive and Specific Detection of Cocaine Using Supramolecular Aptamer Fragments/Target Complex by Electrochemical Impedance Spectroscopy. Talanta, 2012, 92, 65-71.