李徐奇

研究领域（方向）

学术及科研成果、专利、论文

[1] Cancan Zhou, Weikun Qian, Jiguang Ma, Liang Cheng, Zhengdong Jiang, Bin Yan, Jie Li, Wanxing Duan, Liankang Sun, Junyu Cao, Fengfei Wang, Erxi Wu, Zheng Wu,  Qingyong Ma, Xuqi Li*. Resveratrol enhances the chemotherapeutic response and reverses the stemness induced by gemcitabine in pancreatic cancer cells via targeting SREBP1. Cell Proliferation. DOI:10.1111/cpr.12514. (IF=4.936)

[2] Yuanhong Chang, Jie Zhang, Cancan Zhou, Guanglin Qiu, Guanghui Wang, Shufeng Wang, Xinming Chang, Xuqi Li*, Lin Fan*. Long non-coding RNA FOXD2-AS1 plays an oncogenic role in hepatocellular carcinoma by targeting miR‑206. Oncology Reports. 2018; 40(6): 3625-3634. (IF=2.976)

[3]Yuanhong Chang, Cancan Zhou, Lin Fan, Guanglin Qiu, Guanghui Wang, Guangbing Wei, Xinming Chang, Xuqi Li*. Upregulation of microRNA‑300 induces the proliferation of liver cancer by downregulating transcription factor FOXO1. Oncology Reports. 2018; 40(6): 3561-3572. (IF=2.976)

[4]Pengbo Jia, Guangbing Wei, CanCan Zhou, Qi Gao, Yunhua Wu, Xuejun Sun, Xuqi Li*. Up-regulation of miR-212 inhibits migration and tumorigenicity and inactivates Wnt/β-catenin signaling in human hepatocellular carcinoma. Technology in Cancer Research & Treatment. 2018; 37(1):69. (IF=2.204)

[5] Guangbing Wei, Yunhua Wu, Qi Gao, Cong Shen, Zilu Chen, Kang Wang, Junhui Yu, Xuqi Li*, Xuejun Sun*. Gallic acid attenuates postoperative intra-abdominal adhesion by inhibiting the inflammatory reaction in a rat model. Medical science monitor. 2018; 24: 827-838. (IF=1.403)

[6] Qi Gao, Guangbing Wei, Yunhua Wu, Na Yao, Cancan Zhou, Kai Wang, Kang Wang, Xuejun Sun, Xuqi Li*. Paeoniflorin prevents postoperative peritoneal adhesion formation in an experimental rat model. Oncotarget. 2017. 8(55): 93899. (IF=5.168)

[7]Lina Qiao, Jianbao Zheng, Xianzhen Jin, Guangbing Wei, Guanghui Wang, Xuejun Sun, Xuqi Li*. Ginkgolic Acid Inhibits the Invasiveness of Colon Cancer Cells through AMPK Activation. Oncology Letters. 2017. 14(11): 5831-5838. (IF=1.39)

[8] Guangbing Wei, Yunhua Wu, Qi Gao, Cancan Zhou, Kai Wang, Cong Shen, Guanghui Wang, Kang Wang, Xuejun Sun, Xuqi Li*. Effect of Emodin in Preventing Postoperative Intra-Abdominal Adhesion Formation. Oxidative Medicine and Cellular Longevity. 2017. 2017: 1740317. (IF=4.593)

[9] Yu Yan, Cancan Zhou, Jie Li, Ke Chen, Guanghui Wang, Guangbing Wei, Mingwei Chen, Xuqi Li*. Resveratrol Inhibits Hepatocellular Carcinoma Progression Driven by Hepatic Stellate Cells by Targeting Gli-1. Molecular and Cellular Biochemistry. 2017. 434(1-2): 17-24 (IF=2.669)

[10] Yanping Liu, Wei Hong, CanCan Zhou, Zhengdong Jiang, Guanghui Wang, Guangbing Wei, Xuqi Li*. miR-539 inhibits FSCN1 expression and suppresses hepatocellular carcinoma migration and invasion. Oncology Reports. 2017. 37(5): 2593-2602. (IF=2.662)

[11] Guangbing Wei, Cancan Zhou, Guanghui Wang, Lin Fan, Kang Wang, Xuqi Li*. Keratinocyte Growth Factor Combined with a Sodium Hyaluronate Gel Inhibits Postoperative Intra-Abdominal Adhesions. International Journal of Molecular Sciences. 2016. 17(10): 1611. (IF=3.226)

[12] Wei G, Chen X, Wang G, Fan L, Wang K, Li X*. Effect of resveratrol on the prevention of intra-abdominal adhesion formation in a rat model. Cellular physiology and biochemistry. 2016. 39(1): 33-46. (IF=5.104)

[13] Cancan Zhou, Pengbo Jia, Zhengdong Jiang, Ke Chen, Guanghui Wang, Kang Wang, Guangbing Wei, Xuqi Li*. Preventive effects of the intestine function recovery decoction, a traditional Chinese medicine, on postoperative intra-abdominal adhesion formation in a rat model. Evidence-Based Complementary and Alternative Medicine. 2016. 2016: 1621894. (IF=1.74)

[14] Guanglin Qiu#, Xuqi Li#, Chao Wei#, Che Xiangming, Shicai He, Jing Lu, Shufeng Wang, Ke Pang, and Lin Fan. The prognostic role of SIRT1-autophagy axis in gastric cancer. Disease Markers. 2016(2016): 6869415. (IF=2.348) (Co-first Author)

[15] Qiu G, Li X^#, Che X, Wei C, He S, Lu J, Jia Z, Pang K, Fan L. SIRT1 is a regulator of autophagy: Implications in gastric cancer progression and treatment. FEBS letters. 2015. 589(16): 2034-2042. (IF=3.519)

[16] Wei G, Chen X, Wang G, Jia P, Xu Q, Ping G, Wang K, Li X*. Inhibition of cyclooxygenase-2 prevents intra-abdominal adhesions by decreasing activity of peritoneal fibroblasts. Drug design, development and therapy. 2015. 9: 3083-3098. (IF=2.881)

[17] Lei J, Fan L, Wei G, Chen X, Duan W, Xu Q, Sheng W, Wang K, Li X*. Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer. Tumour biology. 2015. 36(4): 3119-3126. (IF=2.926)

[18] Xu Q, Ma J, Lei J, Duan W, Sheng L, Chen X, Hu A, Wang Z, Wu Z, Wu E, Ma Q, Li X*. α-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by down regulating the PI3K/Akt pathway. BioMed research international. 2014. 2014: 546353. (IF= 2.134)

[19] Li X^#, Li P, Chang Y, Xu Q, Wu Z, Ma Q, Wang Z. The SDF-1/CXCR4 axis induces epithelial–mesenchymal transition in hepatocellular carcinoma. Molecular and cellular biochemistry. 2014. 392(1-2): 77-84. (IF=2.613)

[20] Li X^#, Wang Z, Ma Q, Xu Q, Liu H, Duan W, Lei J, Ma J, Wang X, Lv S, Han L, Li W, Guo J, Guo K, Zhang D, Wu E, Xie K. Sonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancer. Clinical cancer research. 2014. 20(16): 4326-4338. (IF=8.738)

[21] Wang Z, Li J, Chen X, Duan W, Ma Q, Li X*. Disrupting the balance between tumor epithelia and stroma is a possible therapeutic approach for pancreatic cancer. Medical science monitor. 2014. 20: 2002-2006. (IF=1.403)

[22] Duan W, Chang Y, Li R, Xu Q, Lei J, Yin C, Li T, Wu Y, Ma Q, Li X*. Curcumin inhibits hypoxia inducible factor‑1α‑induced epithelial‑mesenchymal transition in HepG2 hepatocellular carcinoma cells. Molecular medicine reports. 2014. 10(5): 2505-2510. (IF=1.559)

[23] Li X^#, Ma G, Ma Q, Li W, Liu J, Han L, Duan W, Xu Q, Liu H, Wang Z, Sun Q, Wang F, Wu E. Neurotransmitter substance P mediates pancreatic cancer perineural invasion via NK-1R in cancer cells. Molecular cancer research. 2013. 11(3): 294-302. (IF=4.51)

[24] Li X^#, Ma Q, Xu Q, Duan W, Lei J, Wu E. Targeting the cancer-stroma interaction: a potential approach for pancreatic cancer treatment. Current pharmaceutical design. 2012. 18(17): 2404-2415. (IF=3.052)

[25] Li X^#, Ma Q, Xu Q, Liu H, Lei J, Duan W, Bhat K, Wang F, Wu E, Wang Z. SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway. Cancer letters. 2012. 322(2): 169-176. (IF=5.992)

[26]Li X^#, Ma Q, Duan W, Liu H, Xu H, Wu E. Paracrine sonic hedgehog signaling derived from tumor epithelial cells: a key regulator in the pancreatic tumor microenvironment. Critical reviews in eukaryotic gene expression. 2012. 22(2): 97-108. (IF=1.66)

  联系地址：西安交通大学第一附属医院普通外科