姓名：

党永辉

一级学科：

法医学

照片：

研究领域（方向）：

1.法医精神病学与心理学

2.法医毒理学与毒物分析

3.重性精神障碍的神经生物学

个人及工作简历：

1998年毕业于原西安医科大学临床医学专业后留校任教至今；

2006.10-2008.06于中国科学院心理研究所行为遗传中心博士生访学；

2011.08-2012.07作为中央和国家机关、中央企业第七批援疆干部担任新疆维吾尔医学专科学校教务处副处长；

2017.11-2018.11丹麦Aarhus大学访问学者。

累计主持各级各类科研基金9项，其中国家自然科学基金面上项目3项；目前发表SCI收录期刊论文48篇，其中通讯作者文章23篇，第一作者文章8篇；参编教材、专著著作9部。2014年获高等教育国家级教学成果奖二等奖（排名第四）及“第七批中央和国家机关、中央企业优秀援疆干部人才”称号，荣记二等功。

担任SCI收录期刊Frontiers in Behavioral Neuroscience、PLoS ONE、Medicine编委；Medline收录期刊《法医学杂志》编委；《中国医学伦理学》杂志青年编委；陕西省法医学会理事；陕西省性学会理事，陕西省性学会性心理专业委员会副主任委员；中华医学会精神医学分会司法精神医学组委员，西安市医学会第六届精神病学分会委员；中国药物滥用防治协会青年专家委员会委员。

主要科研项目：

1. 2011年陕西省科学技术研究发展计划项目《甲基苯丙胺依赖大鼠腹外侧眶皮层表观遗传机制研究》（No.2011K15-01-03）；

2. 2012年国家自然科学基金资助面上项目《HINT1蛋白缺乏影响甲基苯丙胺成瘾行为的细胞与分子机制》（No.81171262）；

3. 2014年国家自然科学基金资助面上项目《Hint-/-小鼠精神分裂样表型筛选及其VTA-NAc-PFC通路神经可塑性机制研究》（No.81371473）；

4. 2016年陕西省自然科学基础研究计划面上项目《氧化锆金属泡沫3D细胞培养体系在实验性帕金森病模型中的应用》（No.2016JM8078）；

5. 2017年国家自然科学基金资助面上项目《BDNF及GDNF干预吗啡成瘾行为的基因治疗策略与机制研究》（No.81771435）

学术集科研成果、专利、论文：

Corresponding author

1. A meta-analysis of emotional disorders as possible risk factors for chronic periodontitis. Medicine. 2018

2. Yuan Zhou, Hao-kang Zhang, Fei Liu1, Gang Lei, Peng Liu, Tong Jiao Yong-hui Dang. Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice. Front Behav Neurosci, 2018

3. HINT1 in Neuropsychiatric Diseases: A Potential Neuroplastic Mediator. Liu P, Liu Z, Wang J, Ma X, Dang Y*. Neural Plast. 2017:5181925.

4. Sun LK, Liu P, Liu F, Zhou Y, Chu Z, Li YQ, Chu G, Zhang Y, Wang JB, Dang YH*. Effects of Hint1 deficiency on emotional-like behaviors in mice under chronic immobilization stress. Brain Behav. 2017, 23;7(10):e00831.

5. Liu F, Liu YP, Lei G, Liu P, Chu Z, Gao CG, Dang YH*.Antidepressant effect of recombinant NT4-NAP/AAV on social isolated mice through intranasal route. Oncotarget. 2017, 8(6):10103-10113.

6. Liu F, Lei G, Jia XD, He SY, Dang YH*. Worldwide trends of forensic dentistry: a 20-year bibliometric analysis in Pubmed. Rom J Leg Med. 2016, 24(3):236-241

7. Liu P, Xing B, Chu Z, Liu F, Lei G, Zhu L, Gao Y, Chen T, Dang, YH*. The DopamineD3 Receptor Knockout Mice Exhibit Abnormal Nociception in a Sex-Different Manner. J Neurosci Res. 2017, 95(7):1438-1445.

8. Liu F, Ma J, Liu P, Chu Z, Lei G, Jia XD, Wang JB, Dang YH*. Hint1 gene deficiency enhances the supraspinal nociceptive sensitivity in mice. Brain Behav. 2016, 6(8):e00496.

9. Zhao Y, Liu P, Chu Z, Liu F, Han W, Xun X, Dang YH*. Electrolytic Lesions of the bilateral ventrolateral orbital cortex inhibit methamphetamine-associated contextual memory formation in rats. Brain Res. 2015, 22:1624:214-21.

10. Xing B, Liang XP, Liu P, Zhao Y, Chu Z, Dang YH*.Valproate Inhibits Methamphetamine Induced Hyperactivity via Glycogen Synthase Kinase 3β Signaling in the Nucleus AccumbensCore. PLoS One. 2015, 10(6):e0128068.

11. Liu ZW, Li WQ, Wang JK, Ma XC, Liang C, Liu P, Chu Z, Dang YH*.Zirconium oxide ceramic foam: a promising supporting biomaterial for massive production of glial cell line-derived neurotrophic factor. J Zhejiang UnivSci B. 2014,15(12):1013-22.

12. Xing B, Liu P, Xu WJ, Xu FY, Dang YH*.Effect of Microinjecting of 5-aza-2-deoxycytidine into Ventrolateral Orbital Cortex on Depressive-like Behavior in Rats. Neurosci Lett. 2014, 574:11-4.

13. Liu F, Ma J, Zhang H, Liu P, Liu YP, Xing B, Dang YH*.Fluoride exposure during development affects both cognition and emotion in mice. Physiol Behav. 2014, 124:1-7.

14. Xing B, Liu P, Jiang WH, Liu F, Zhang H, Cao GF, Chen T, Dang YH*.Effects of immobilization stress on emotional behaviors in dopamine D3 receptor knockout mice. Behav Brain Res. 2013, 243:261-6.

Co-corresponding author

15. Li JP, Liu P, Lei G, Chu Z, Liu F, Shi CF, Dang YH*, Chen T*. The Role of HINT1 in Methamphetamine-induced Conditioned Place Preference. Neurotox Res. 2017, Accepted.

16. Li BJ, Liu P, Chu Z, Shang Y, Huan MX, Dang YH*, Gao CG*. Social isolation induces schizophrenia-like behavior potentially associated with HINT1, NMDA receptor 1, and dopamine receptor 2. Neuro report. 2017, 28(8):462-469.

17. Ma XC, Liu P, Zhang XL, Jiang WH, Jia M, Wang CX, Dong YY, Dang YH*, Gao CG*. Intranasal Delivery of Recombinant AAV Containing BDNF Fused with HA2TAT: a Potential Promising Therapy Strategy for Major Depressive Disorder. Sci Rep. 2016,6:22404.

18. Ma XC, Chu Z, Zhang XL, Jiang WH, Jia M, Dang YH*, Gao CG*. Intranasal Delivery of Recombinant NT4-NAP/AAV Exerts Potential Antidepressant Effect. Neurochem Res. 2016, 41(6):1375-80.

19. Ma J, Liu F, Liu P, Dong YY, Chu Z, Hou TZ*, Dang YH*. Impact of early developmental fluoride exposure on the peripheral pain sensitivity in mice. Int J Dev Neurosci. 2015, 47(Pt B):165-71.

20. Liu Z, Cai H, Zhu H, Toque H, Zhao N, Qiu C, Guan G, Dang Y*, Wang J*.Protein kinase RNA-like endoplasmic reticulum kinase (PERK)/calcineurin signaling is a novel pathway regulating intracellular calcium accumulation which might be involved in ventricular arrhythmias in diabetic cardiomyopathy. Cell Signal. 2014, 26(12):2591-2600.

21. ZhaoY, XingB, DangYH*, Qu CL, ZhuF, Yan CX*.Microinjection of ValproicAcid into the Ventrolateral Orbital Cortex EnhancesStress-Related Memory Formation. PLoS One, 2013, 8(1): e52698.

22. Xing B, Zhao Y, Zhang H, Dang Y*, Chen T*, Huang J, Luo Q. Microinjection of valproic acid into the ventrolateral orbital cortex exerts an antidepressant-like effect in the rat forced swim test. Brain Res Bull, 2011,85(3-4):153-157.

23. Ma XC, Jiang D, Jiang WH, Wang F, Jia M, Wu J, Hashimoto K, Dang YH*, Gao CG*.Social isolation-induced aggression potentiates anxiety and depressive-like behavior in male mice subjected to unpredictable chronic mild stress. PLoS One, 2011, 6(6): e20955.

First Author

24. Dang YH, Liu P, Ma R, Chu Z, Liu YP, Wang JB, Ma XC, Gao CG.HINT1 is involved in the behavioral abnormalities induced by social isolation rearing. Neurosci Lett. 2015, 21:607:40-5.

25. Dang YH, Ma XC, Zhang JC, Ren Q, Wu J, Gao CG, Hashimoto K. Targeting of NMDA Receptors in the Treatment of Major Depression. Curr Pharm Des. 2014, 20(32):5151-9.

26. Dang YH, Zhao Y, Xing B, Zhao XJ, Huo FQ, Tang JS, Qu CL, Chen T. The role of dopamine receptors in ventrolateral orbital cortex-evoked anti-nociception in a rat model of neuropathic pain. Neuroscience, 2010, 169(4):1872-80.

27. Dang YH, Xing B, Zhao Y, Zhao XJ, Huo FQ, Tang JS, Qu CL, Chen T. The role of dopamine receptors in ventrolateral orbital cortex-evoked antinociceptionin a rat formalin test model. Eur J Pharmacol, 2011,657(1-3):97-103.

Co-First Author

28. Ma XC*, Dang YH*, Jia M, Ma R, Wang F, Wu J, Gao CG, Hashimoto K. Long-Lasting Antidepressant Action of Ketamine, but Not Glycogen Synthase Kinase-3 Inhibitor SB216763, in the Chronic Mild Stress Model of Mice. PLoS One, 2013, 8(2):e56053.

29. Zheng YM*,Dang YH*,Qiu S, Qi YP, Xu YP, Sai WJF. Differentiation and characteristics of the enhanced green fluorescent protein gene transgenic goat neural stem cells cultured in attached and non-attached plates. Cell Biol Int, 2011, 35(8):849-56.

30. Zheng YM*,Dang YH*,Xu YP, Sai WJF, An ZX. Differentiation of AFS cells derived from the EGFP gene transgenic porcine fetuses. Cell Biol Int, 2011, 35(8):835-9.

31. Chen F*, Dang YH*, Yan CX, Liu YL, Deng YJ, Fulton DJ, Chen T. Sequence-length variation of mtDNA HVS-I C-stretch in Chinese ethnic groups. J Zhejiang Univ Sci B, 2009, 10(10):711-20.

教材与专著：

1.与活体有关的鉴定——司法精神病学鉴定（1～11）．见：张秦初主编．临床法医学鉴定问答．北京：人民卫生出版社，2002．142～154.

2.心理保健方法；学习和工作中的心理保健；现代生活现象与心理保健．见：姚斌主编．现代人的心理保健——走出心理困惑．北京：人民卫生出版社，2001．75～105，320～375.

3.（第七章）干细胞的应用；（附录三）治疗性克隆之争.见：郑月茂、张雅蓉主编.干细胞、克隆与转基因.北京：北京科学技术出版社，2011. 92~121，260~262.

4.（第一章）基因与基因工程.见：郑月茂主编.转基因克隆动物理论与实践.北京：科学出版社，2012. 13~62.

5.（第四章4.2）光遗传学技术在成瘾研究中的应用；（第十四章14.2）精神外科治疗.见：李生斌主编.成瘾基因组学.西安：西安交通大学出版社，2016. 165～172，410～416.

6.（第19章）精神疾病的司法鉴定．见：李生斌主编．现代实用法医学．西安：西安交通大学出版社，2010．309~320.

7.（第五章）毒品中毒．见：朱少华主编．法医毒理学实验指导．北京：人民卫生出版社，2016. 38~48.

8.（第八章）法医心理学.见：李生斌主编.法医学.北京：人民卫生出版社，2017.

联系方式

电子邮箱：psydyh@xjtu.edu.cn

联系电话：

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联系地址：西安市雁塔西路76号