摘要：通过研究4种制粒工艺的工作原理和存在的优缺点,对制得安全气囊气体发生剂颗粒的粒度分布、松散密度、振实密度以及药片质量差异极值、侧压强度进行测试和分析,对比4种工艺颗粒的参数差异。结果表明:喷雾制得的气体发生剂颗粒粒度分布较集中,休止角较小,压缩度也较小,压片后的药片质量差异极值也较小,侧压强度较大;颗粒的休止角越小,压缩度越小,药片的质量差异极值越小,颗粒的压缩度与药片的侧压强度呈线性关系。

关键词：制粒；气体发生剂；休止角；压缩度

Abstract：By studying the working principles and disadvantages of four kinds of granulating technologies,the particle size distribution,bulk density,tap density,as well as extreme difference of tablet weigh and compressive strength of the prepared airbag gas generent particles were tested and analyzed. The difference among the parameters of particles in the four kinds of technologies was compared. The results show that the size distribution of the airbag gas generent particles prepared by spray system is more concentrated. The degree of compression and tablet weight variation extreme value of tablets pressed by particles are less,and the lateral pressure strength is greater. The less the angle of repose is,the less the degree of compression is,and the less the extreme difference of tablet weigh is. The particle degree of compression and compressive strength of tablets appear linear relationship.

Keywords: granulate； gas generent；angle of repose；degree of compression