Aiming at the characteristics of experimental subjects of materials science and chemistry, some design, exploration and practice in the online and offline hybrid teaching mode of “laboratory safety” were made by combining the construction background and content of “laboratory safety” course and focusing on the studentcentered teaching concept.Taking the theoretical teaching content of “occurrence and prevention of explosion accidents of dangerous chemicals” and the practical teaching content of “cardiopulmonary resuscitation” as examples, this paper discusses how to realize the combination of network platform, classroom teaching platform and practical teaching platform through the mixed instructional design from the preclass, inclass and afterclass.

laboratory safety; course construction; online and offline; mixed instructional design