学历：博士，
职称：教授
所属部门：生物技术系，招生专业：（博士、硕士）
联系电话：0538-8249942，E-mail：zhongxinguo@sdau.edu.cn
个人简介
郭忠新，男，生于1975年9月，教授，博导。2010年获University of Oklahoma-Norman植物学博士学位，美国University of California-Riverside博后及副研究员。曾入选福建省领军人才“百人计划”、“闽江学者”特聘教授和省B类高层次人才。主要研究拟南芥、番茄和水稻抗病毒免疫作用机理及应用，研究课题得到国家自然基金及省级重点基金支持，研究成果发表在顶级期刊Nature Reviews Immunology和国际一流期刊PNAS、Pant Cell 、Plant Physiology、PLOS Pathogens、Horticulture Research、Nature Communications等。
研究方向
1、重大番茄病毒病抗性基因的挖掘、作用机理解释及育种应用
2、拟南芥中RNAi介导的抗病毒免疫作用机理
3、新型蚜虫传水稻病毒RLTV和RITV与水稻互作
发表论文
Zhongxin Guo, Yang Li, Shou-Wei Ding. (2019) Small RNA-based antimicrobial immunity, Nature Reviews Immunology, 19, 31-44. (IF 76)
Yan WK, Zhu Y, Zou CW, Liu W, Jia B, Niu J, Zhou Y, Chen B, Li R, Ding SW, Wu Q, Guo ZX. (2024) Virome Characterization of Native Wild‐Rice Plants Discovers a Novel Pathogenic Rice Polerovirus With World‐Wide Circulation, Plant, Cell & Environment, 1-16, doi.org/10.1111/pce.15204. (IF 6.1)
Yan W, Zhu Y, Liu W, Zou C, Jia B, Chen ZQ, Han Y, Wu J, Yang DL, Zhang Z, Xie L, Chen B, Li R, Ding S-W, Wu Q, Guo Zhongxin. (2023) Discovery of aphid-transmitted rice tiller inhibition virus from native plants by small RNA sequencing, PLOS Pathogens. doi.org/10.1371/journal.ppat.1011238. (IF 6.7)
Zhao LL, Chen YF, Xiao XM, Gao HY, Cao JM, Zhang ZK, Guo Zhongxin. (2023) AGO2a but not AGO2b mediates antiviral defense against the infection of wildtype Cucumber mosaic virus in tomato, Horticulture Research, uhad043, doi.org/10.1093/hr/uhad043. (IF 8.7)
Xu Q, Shen L, Jin L, Wang M, Chang F, Guo Zhongxin. (2022). Comparative transcriptome analysis of CMV or 2b-deficient CMV-Infected dcl2dcl4 reveals the effects of viral infection on symptom induction in Arabidopsis thaliana. Viruses, 14(7), 1582. (IF 4.7)
Liying Jin, Mengna Chen, Meiqin Xiang, Zhongxin Guo. (2022) RNAi-based antiviral innate immunity in plants, Viruses, 14, 432. (IF 4.7)
Zhongxin Guo, Xian-Bing Wang, Wan-Xiang Li, and Shou-Wei Ding. (2019) A sensitized genetic screen to identify novel components and regulators of the host antiviral RNA interference pathway. Methods of Molecular Biology, 2028: 215-229.
Zhongxin Guo, Jinfeng Lu, Xianbing Wang, Wanxiang Li, Shou-Wei Ding. (2017) Lipid flippases promote antiviral silencing and the biogenesis of viral and host siRNAs in Arabidopsis. Proc Natl Acad Sci U S A 114, 1377-1382. (IF 11.1)
Zhongxin Guo*, Xianbing Wang*, Ying Wang, Wanxiang Li, Amit Gal-On, Shou-Wei Ding. (2018) Identification of a new host factor required for antiviral silencing and amplification of viral siRNAs. Plant Physiology, 176, 1587-1597. (IF 7.4)
Zhongxin Guo, Shozo Fujioka, Sen Miao, Blancaflor Elison, Xiaoping Gou, Jia Li. (2010) TCP1 modulates Brassinosteroid biosynthesis by regulating the expression of the key biosynthetic enzyme gene DWARF4 in Arabidopsis thaliana. Plant Cell, 22, 1161-1173. (IF 11.6)
Qingfeng Niu#, Zhe Song#, Kai Tang, Lixian Chen, Lisi Wang, Ting Ban, Zhongxin Guo, Chanhong Kim, Heng Zhang, Cheng-Guo Duan, Huiming Zhang, Jian-Kang Zhu, Jiamu Du*, Zhaobo Lang*. (2021) A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation. Nature Communications, 12(1):3367. (IF 16.6)
Zhong-Qi Chen, Jian-Hua Zhao, Qian Chen, Zhong-Hui Zhang, Jie Li, Zhongxin Guo, Qi Xie, Shou-Wei Ding, Hui-Shan Guo*. (2020) DNA Geminivirus Infection Induces an Imprinted E3 Ligase Gene to Epigenetically Activate Viral Gene Transcription. Plant Cell, 32(10):3256-3272. (IF 11.6)
Kezhi Zheng, Lili Wang, Longjun Zeng, Dachao Xu, Zhongxin Guo, Xiquan Gao, Dong-Lei Yang*. (2021) The effect of RNA polymerase V on 24-nt siRNA accumulation depends on DNA methylation contexts and histone modifications in rice. PNAS, 118(30): e2100709118. (IF 11.1)
