学历:博士研究生        所属部门: 生物技术系

职称:教授           招生专业: 细胞生物学（博士、硕士）

联系电话: 0538-8241245      E-mail:zhchx@sdau.edu.cn 

个人简介

朱常香，博士，教授，博士生导师。现任生命科学学院副院长，学院教授委员会委员，入选学校“1512”工程第二层次，山东省植物病理学会常务理事。主要从事植物保护生物技术研究。近年来，主持国家自然科学基金3项，国家转基因生物新品种培育重大专项子课题1项，山东省自然科学基金4项，省、市良种工程项目4项，横向课题2项。在Molecular Plant Pathology、Frontiers in Plant Science等国内外核心期刊发表研究论文100余篇，其中SCI收录60余篇；获授权发明专利4项；获得省科学技术进步二等奖1项。主持省级一流课程1门、省级精品课程1门、国家级、省级及校级质量工程和教改项目5项；主编和副主编“十三五”规划教材2部，发表教研论文8篇；获山东省教学成果特等奖1项、一等奖1项、二等奖2项、校级教学成果奖4项。

个人荣誉

山东省大中专学生志愿者暑期“三下乡”社会实践活动优秀指导教师

山东农业大学“十大师德标兵”

教学工作

承担本科生《农业生物技术》、《基因工程综合实验》等课程。

研究方向

1.植物与病毒互作分子生物学：探讨植物与病毒间的防御与反防御机制，分析病毒-昆虫-寄主植物间的多重互作关系，为植物病害防控提供有效策略。

2.植物抗逆基因工程：探讨植物抗病虫、抗盐抗旱的分子机理，分离克隆抗逆相关基因，利用转基因技术培育抗逆作物新品种。

科研项目

1.山东省自然科学基金面上项目：水稻黑条矮缩病毒P9-1蛋白与灰飞虱RPN8蛋白互作调控病毒在介体中传播的分子机理研究，2019-2022，20万元。

2.转基因生物新品种培育重大专项：抗病转基因水稻新品种培育（子课题）, 2016-2020，337.31万元。

3.国家自然科学基金面上项目：嵌合基因、保守片段的序列特征对RNA介导的多病毒抗性的影响及其机理研究，2013-2016，70万元。

4.国家自然科学基金面上项目：RNA介导的病毒抗性中的位置效应研究，2008-2010，26万元。

5.山东蓬勃生物科技有限公司横向课题：ZNC免疫诱抗剂的抗植物病毒机理研究；2020-2024，20万元

发表论文

1. Kaijie Shang, Yang Xu, Weilin Cao,  Xiaoying Xie, Yanru Zhang, Jingfeng Zhang, Hongmei Liu, Shumei Zhou,  Xiaoping Zhu*, Changxiang Zhu*. Potato (Solanum tuberosum L.) non-specifc lipid transfer protein StLTP6 promotes viral infection by inhibiting virus-induced RNA silencing. Planta, 2022, 256: 54

2. Weilin Cao, Junyuan Ca, Jiaqi Gao, Ruolin Wang, Ying Li, Changyuan Li, Liming Gan*, Changxiang Zhu*.Genome wide identification and association analysis for virus responsive lncRNAs in rice (Oryza sativa L.). Plant Growth Regulation, 2022, 98: 65-76.

3. Ying Li, Lifei Zhu, Jiaqi Gao, Haoran Ma, Changyuan Li, Yunzhi Song, Xiaoping Zhu* and Changxiang Zhu*. Silencing suppressors of rice black-streaked dwarf virus and rice stripe virus hijack the 26S proteasome of Laodelphax striatellus to facilitate virus accumulation and transmission. Pest Management Science, 2022, 78 (7): 2940-2951.

4. Weilin Cao, Ruolin Wang, Junyuan Cao,  Jiaqi Gao, Xuechen Zhao, Liming Gan, Changxiang Zhu*. Genome-wide identification and characterization of long noncoding RNAs in maize under rice black streaked dwarf virus infection. Plant Pathology, 2022, 71: 741–749.

5. Yang Xu, Kaijie Shang, Chenchen Wang, Zipeng Yu, Xuechen Zhao, Yunzhi Song, Fanxiao Meng, Changxiang Zhu*. WIPK–NtLTP4 pathway confers resistance to Ralstonia solanacearum in tobacco. Plant Cell Reports, 2022,41(1): 249-261

6. Ying Li, Jinwen Du, Yang Xu, Jiaqi Gao, Yunzhi Song & Changxiang Zhu*. RNAi silencing of Rice black-streaked dwarf virus P10 and two insect vector genes to reduce virus transmission protects rice plants against RBSDV. Journal of Plant Interactions, 2021, 16(1): 83-92.

7. Weilin Cao, Liming Gan, Chenchen Wang, Xuechen Zhao, Mingyu Zhang, Jinwen Du, Shumei Zhou* and Changxiang Zhu*. Genome-Wide Identification and Characterization of Potato Long Non-coding RNAs Associated With Phytophthora infestans Resistance. Frontiers in Plant Science, 2021, 12: 619062.

8. Chune Peng, Qingbin Wang, Runmiao Jiao, Yingying Xu, Naihan Han,Wenshuang Wang, Changxiang Zhu⁎, Fuchuan Li⁎. A novel chondroitin sulfate E from Dosidicus gigas cartilage and its antitumor metastatic activity. Carbohydrate Polymers, 2021, 262 (15): 117971.

9. Chune Peng , Ailing Zhang, Qingbin Wang, Yunzhi Song , Min Zhang , Xinhua Ding , Yang Li, Quanzheng Geng and Changxiang Zhu* . Ultrahigh-activity immune inducer from Endophytic Fungi induces tobacco resistance to virus by SA pathway and RNA silencing, BMC Plant Biology, 2020, 20:169.

10. Weilin Cao, Liming Gan, Kaijie Shang, Chenchen Wang, Yunzhi Song, Hongmei Liu, Shumei Zhou, Changxiang Zhu*. Global transcriptome analyses reveal the molecular signatures in the early response of potato (Solanum tuberosum L.) to Phytophthora infestans, Ralstonia solanacearum, and Potato virus Y infection. Planta, 2020, 252: 57.

11. Chenchen Wang, Hongjuan Gao, Zhaohui Chu, Changquan Ji, Yang Xu, Weilin Cao, Shumei Zhou, Yunzhi Song, Hongmei Liu*, Changxiang Zhu*. A nonspecific lipid transfer protein, StLTP10, mediates resistance to Phytophthora infestans in potato . Molecular Plant Pathology. 2020;00:1–16.

12. Yang Xu, Xinxin Zheng, Yunzhi Song, Lifei Zhu, ZipengYu, Liming Gan, Shumei Zhou, Hongmei Liu, Fujiang Wen & Changxiang Zhu*. NtLTP4, a lipid transfer protein that enhances salt and drought stresses tolerance in Nicotiana tabacum. Scientific Reports, 2018, 8:8873.

13. Ru Yu, Caixia Chen, Weilin Cao, Hongmei Liu, Shumei Zhou, Yunzhi Song* ,Changxiang Zhu*. Highdegree and broadspectrum resistance mediated by a combination of NIb siRNA and miRNA suppresses replication of necrotic and common strains of potato virus Y. Archives of Virology , 2018, 163 (11): 3073–3081.

14. Xiufang Liu, Yunzhi Song, Fangyu Xing, Ning Wang, Fujiang Wen, Changxiang Zhu*. GhWRKY25, a group I WRKY gene from cotton, confers differential tolerance to abiotic and biotic stresses in transgenic Nicotiana benthamiana. Protoplasma. 2016, 253（5）：1265–1281.

15. Yang Li, Wenzhao Tang, Jing Chen, Ru Jia, Lianjie Ma, Shaoli Wang, Jiao Wang, Xiangling Shen, Zhaohui Chu, Changxiang Zhu*, and Xinhua Ding*. Development of Marker-Free Transgenic Potato Tubers Enriched in Caffeoylquinic Acids and Flavonols. Journal Of Agricultural And Food Chemistry, 2016, 64(14):2932-2940.

16. Lin Ma, Xu Huang, Ru Yu, Xiuli Jing, Jie Xu, ChangAi Wu, ChangXiang Zhu*, HongMei Liu*. Elevated Ambient Temperature Differentially Affects Virus Resistance in two tobacco species . Phytopathology, 2016, 106(1): 94-99.