学  历

博士

职  称

教授

所属部门

生物化学与分子生物学系

招生专业

生物化学与分子生物学（硕士、博士）

联系方式

电话: 0538-8242894   E-mail: cczheng@sdau.edu.cn

个人简介

郑成超，博士，教授，博士生导师。现任作物生物学国家重点实验室副主任。2002年至2018年任生命科学学院院长。2004年入选国家“新世纪百千万人才工程”国家级人才，2007年入选教育部“长江学者创新团队”带头人，2008年入选山东省有突出贡献的中青年专家，2012年入选泰山学者特聘教授。《植物学报》、《农业生物技术学报》编委。1982年毕业于山东农业大学留校任教至今，先后获山东农业大学农学硕士和中国农业大学理学博士学位。1989年赴丹麦哥本哈根研修种子技术，1992年至1996年赴美国加利福尼亚大学戴维斯分校植物生物学系留学，主要从事植物分子生物学方面的研究。2001年赴美国北卡罗莱纳大学合作研究, 主要进行了转基因表达调控的研究。围绕植物抗逆性的分子调控，近年来主持承担了国家“863”、国家“973”、国家转基因植物研究专项和国家自然科学基金等多项课题。在《Molecular Cell》、《Nucleic Acids Research》、《Plant Physiology》和《中国科学》等国内外著名学术刊物上发表论文80多篇。“植物应答温度和高盐胁迫基因的挖掘和调控机制研究”获2015年山东省自然科学二等奖。

教学工作

1.本科生《Gene cloning and DNA analysis》

2.硕士生《生物化学与分子生物学专业讨论》

3.博士生《生物化学与分子生物学专题讨论》

研究方向

 1.植物重要功能基因的克隆、鉴定与利用：以重要农作物玉米、棉花、烟草以及模式植物拟南芥为研究材料，利用正向和反向遗传学策略，克隆与作物抗逆性等密切相关的功能基因，探讨这些基因的表达模式及其调控机制，研究其在作物遗传改良上的利用价值，获得拥有自主知识产权的基因资源。

 2.基因表达调控元件的鉴定与应用：主要研究植物组织特异型启动子和诱导型启动子的表达调控机制与应用，探索植物small RNA、DNA甲基化、核基质结合序列MAR（matrix attachment region）在转录水平上对基因表达的调控机制。

科研项目

 1.国家“973”项目子课题：“作物应答盐碱胁迫的分子调控机理” 2012-2016

 2.973计划前期研究专项：“玉米高温干旱抗性关键microRNA基因的分离及功能鉴定” 2014-2016

 3.国家自然科学基金：“拟南芥CCCH 型锌指转录因子a亚家族的生物学功能及其作用机理的研究”2010-2013

 4.国家自然科学基金：“拟南芥miRNA169家族及靶基因的功能鉴定与分析”2011-2014

 5.国家自然科学基金:“高温胁迫下拟南芥miR400 及其靶基因PPRP 的功能及作用机理研究” 2014-2017

 6.国家自然科学基金:“玉米高温干旱抗性miRNA与lncRNA相互作用机制研究”2016-2019

发表论文

Selected publications (*Corresponding author)

1. Peiyan Guan, Jun Wang, Hui Li, Chen Xie, Shizhong Zhang, Changai Wu, Guodong Yang, Kang Yan, Jinguang Huang* and Chengchao Zheng*. SENSITIVE to SALT1, An ER-localized Chaperone, Positively Regulates Salt Resistance in Arabidopsis. Plant Physiology  2018, 178:1390-1405

2. Yang Xu, Zipeng Yu, Di Zhang, Jinguang Huang, Changai Wu, Guodong Yang, Kang Yan, Shizhong Zhang* and Chengchao Zheng* CYSTM, a Novel Non-Secreted Cysteine-Rich Peptide Family, Involved in Environmental Stresses in Arabidopsis thaliana. Plant and Cell Physiology  2018, 1;59(2):423-438

3. Yuanyuan Li, Huixian Cai, Pu Liu, Chunyan Wang, Huiyang Gao, Changai Wu, Kang Yan, Shizhong Zhang, Jinguang Huang* and Chengchao Zheng*. Arabidopsis MAPKKK18 positively regulates drought stress resistance via downstream MAPKK3. Biochemical and Biophysical Research Communications. 2017, 484 : 292-297

4. Peng-Cheng Li, Jin-Guang Huang1, Shao-Wei Yu, Yuan-Yuan Li, Peng Sun, Chang-Ai Wu and Cheng-Chao Zheng*. Arabidopsis YL1/BPG2 Is Involved in Seedling Shoot Response to Salt Stress through ABI4. Scientific Reports  2016，6:30163

5. Kang Yan, Peng Liu, Chang-Ai Wu, Guo-Dong Yang, Rui Xu, Qian-Huan Guo, Jin-Guang Huang and Cheng-Chao Zheng*. Stress-Induced Alternative Splicing Provides a Mechanism for the Regulation of MicroRNA Processing in Arabidopsis thaliana. Molecular Cell. 2012, 48: 521-531

6. Rui Xu, Yuhan Wang, Hao Zheng, Wei Lu, Changai Wu, Jinguang Huang, Kang Yan, Guodong Yang and Cheng-Chao Zheng*.  Salt-induced transcription factor MYB74 is regulated by the RNA-directed DNA methylation pathway in Arabidopsis. Journal of Experimental Botany 2015, 66(19):5997–6008

7. Fengjuan Jia, Chunyan Wang, Jinguang Huang, Guodong Yang,Changai Wu and Chengchao Zheng*. The SCF E3 ligase AtPP2-B11 plays a positive role in response to salt stress in Arabidopsis. Journal of Experimental Botany  2015, 66(15):4683-97

8.  Changtian Chen, Changai Wu, Jiaming Miao, Yunxue Lei, Dongxiao Zhao, Dan Sun, Guodong Yang, Jinguang Huang and Chengchao Zheng*. Arabidopsis SAG protein containing the MDN1 domain participates in seed germination and seedling development by negatively regulating ABI3 and ABI5. Journal of Experimental Botany  2014，65 (1): 35-45

9. Yanze Li, Fengjuan Jia, Yanli Yu, Lu Luo, Jinguang Huang, Guodong Yang, Changai Wu, Chengchao Zheng*. The SCF E3 Ligase AtPP2-B11 Plays a Negative Role in Response to Drought Stress in Arabidopsis. Plant Molecular Biology Reporter 2014, 32:943-956

10. Fengjuan Jia, Bingjiang Wu, Chengchao Zheng*.Genome-wide identification and characterisation of F-box family in maize. Molecular Genetics and Genomics 2013, 288(11): 559-77

11. Lusha Ji, Rui Xu, Longtao Lu, Jiedao Zhang, Guodong Yang, Jinguang Huang, Changai Wu, Chengchao Zheng. TM6, a novel nuclear matrix attachment region, enhances its flanking gene expression through influencing their chromatin structure. Molecules and Cells 2013, 36:127-137

12. Yingping Gai Chengchao Zheng* A Novel Late Embryogenesis Abundant Like Protein Associated with Chilling Stress in Nicotiana tabacum cv. Bright Yellow-2 Cell Suspension Culture. Molecular and Cellular Proteomics 2011, 10: M111.010363

13. Rui-Rui Xu, Sheng-Dong Qi, Long-Tao Lu, Chang-Tian Chen, Chang-Ai Wu and Cheng-Chao Zheng* A DExD/H box RNA helicase is important for potassium deprivation responses and tolerance in Arabidopsis thaliana. FEBS Journal 2011, 278: 2296-2306

14. Yanjie Li, Yaru Fu, Jinguang Huang, Changai Wu and Chengchao Zheng*Insight into the transcriptional regulation during the early development of the maize brace root. FEBS Journal 2011, 278:156-166

15. Hao Huan, Sheng-Dong Qi, Fang Qi, Chang-Ai Wu, Guo-Dong Yang and Cheng-Chao Zheng*. NtKTI1, a Kunitz trypsin inhibitor with antifungal activity from Nicotiana tabacum, plays an important role in tobacco’s defense response. FEBS Journal 2010, 277:4076-4088

16. Jin-Guang Huang, Mei Yang, Pei Liu, Guo-Dong Yang, Chang-Ai Wu, Cheng-Chao Zheng*. Genome-wide profiling of developmental, hormonal or environmental responsiveness of the nucleocytoplasmic transport receptors in Arabidopsis. Gene. 2010,451:38-44

17. Dongmei Xi, Wushuang Liu, Guodong Yang, Changai Wu, Cheng-chao Zheng*. Seed-specific overexpression of antioxidant genes in Arabidopsis enhances oxidative stress tolerance during germination and early seedling growth. Plant Biotechnology Journal, 2010, 8:796-806

18. Yanjie Li, Yaru Fu, Lusha Ji, Changai Wu, Chengchao Zheng*. Characterization and expression analysis of the Arabidopsis mir169 family. Plant Science 2010,178: 271-280

19. Yu-Tao Yang, Yan-Li Yu, Guo-Dong Yang, Jie-Dao Zhang and Cheng-Chao Zheng*, Tissue-specific expression of the PNZIP promoter is mediated by combinatorial interaction of different cis-elements and a novel ranscriptional factor. Nucleic Acids Research 2009, 37(8):2630-2644

20. Ying-Hui Guo, Yue-Ping Yu, Dong Wang, Chang-Ai Wu, Guo-Dong Yang, Jin-Guang Huang and Cheng-Chao Zheng*. GhZFP1, a novel CCCH-type zinc finger protein from cotton, enhances salt stress tolerance and fungal disease resistance in transgenic tobacco by interacting with GZIRD21A and GZIPR5. New Phytologist 2009, 183: 62-75

21. YanLi Yu, YanZe Li, LingLi Li, JinXing Lin, ChengChao Zheng* Overexpression of PwTUA1, a pollen-specific tubulin gene, increases pollen tube elongation by altering the distribution of α-tubulin and promoting vesicle transport. Journal of Experimental Botany, 2009, 60(9):2737-49

22. Tongtong Xue, Xinzheng Li, Wei Zhu, Changai Wu, Guodong Yang, and Chengchao Zheng*. Cotton metallothionein GhMT3a, a reactive oxygen species scavenger, increased tolerance against abiotic stress in transgenic tobacco and yeast. Journal of Experimental Botany.2009, 60: 339-349

23. Jin-Guang Huang, Mei Yang, Pei Liu, Guo-Dong Yang, Chang-Ai Wu and Cheng-Chao Zheng*. GhDREB1 enhances abiotic stress tolerance, delays GA-mediated development and represses cytokinin signaling in transgenic Arabidopsis. Plant, Cell & Environment, 2009, 32, 1132–1145

24. Jiedao Zhang, Longtao Lu, Lusha Ji, Guodong Yang, Chengchao Zheng*. Functional characterization of a tobacco matrix attachment region-mediated enhancement of transgene expression. Transgenic Research. 2009, 18:377-385

25. Hanhua Liu, Xin Tian, Yanjie Li, Changai Wu and Chengchao Zheng*.Microarray-based analysis of stress-regulated microRNAs in Arabidopsis thaliana. RNA 2008, 14: 836-843

26. Xiyan Yu, Xiufeng Wang, Wenqian Zhang, Tingting Qian, Guimin Tang, Yankui Guo, Chengchao Zheng*. Antisense Suppression of an Acid Invertase Gene (MAI1) in Muskmelon Alters Plant Growth and Fruit Development. Journal of Experimental Botany. 2008, 59(11):2969-77

27. Dong Wang, Yinghui Guo, Changai Wu, Guodong Yang, Yingying Li and Chengchao Zheng*. Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice. BMC Genomics 2008, 9:44

28.  Xin Huang, Wei Zhu, Silan Dai, Shupeng Gai, Guosheng Zheng, Chengchao Zheng*. The involvement of mitochondrial phosphate transporter in accelerating bud dormancy release during chilling treatment of tree peony (Paeonia suVruticosa). Planta 2008, 228(4):545-52

29. Meng-Meng Zhanga, Lu-Sha Ji, Hua Xue, Yu-Tao Yang, Chang-Ai Wu and Cheng-Chao Zheng*. High transformation frequency of tobacco and rice via Agrobacterium-mediated gene transfer by flanking a tobacco matrix attachment region.  Physiologia Plantarum 2007.129: 644-651

30. Da-Peng Shan, Jin-Guang Huang, Yu-Tao Yang, Ying-Hui Guo and Cheng-Chao Zheng*. Cotton GhDREB1 increases plant tolerance to low temperature and is negatively regulated by gibberellic acid. New Phytologist 2007. 176: 70-81