English

Zhenheng Lai

     

I. Contact Information

Zhenheng Lai, PhD, Associate Professor

College of Animal Science and Technology

Northwest A&F University

Yangling, Shaanxi 712100, China

Email: laizhenheng@nwafu.edu.cn

II. Education and Academic Experience

2024.10-current, Associate Professor at College of Animal Science and Technology, Northwest A&F University

2020.09-2024.06, Ph.D. in Animal Nutrition and Feed Science, Northeast Agricultural University, Harbin, China

2017.09-2020.06, Master’s Degree in Animal Nutrition and Feed Science, Northeast Agricultural University, Harbin, China

2013.09-2017.06, Bachelor’s degree in Animal Science, Northeast Agricultural University, Harbin, China

III. Research Interests

(1) Nutritional regulation of swine and research of functional feed additives

(2) Development, optimization and application of feeding-type antimicrobial peptides

Ⅳ. Main publications

(1)Zhenheng Lai, Xiaojie Yuan, Guoyu Li, Hongyu Chen, Baojing Cheng, Anshan Shan*. Nontoxic and Proteolytic-Resistant Self-Assembled Peptide Dendrimer Aggregates to Combat Multidrug-Resistant Gram-negative Bacterial Infections, Chemical Engineering Journal, 2024, 496, 154171.

(2) Zhenheng Lai#, Xiaojie Yuan#, Wenwen Chen, Hongyu Chen, Bowen Li, Zhongpeng Bi, Yinfeng Lyu*, and Anshan Shan*. Design of Proteolytic-Resistant Antifungal Peptides by Utilizing Minimum D-Amino Acid Ratios, Journal of Medicinal Chemistry, 2024, 67, 13, 10891-10905.

(3) Guoyu Li#, Zhenheng Lai#, Anshan Shan*. Advances of Antimicrobial Peptide-Based Biomaterials for the Treatment of Bacterial Infections, Advanced Science, 2023, 2206602.

(4)Zhenheng Lai, Xiaojie Yuan, Hongyu Chen, Yunhui Zhu, Na Dong, Anshan Shan*. Strategies Employed in the Design of Antimicrobial Peptides with Enhanced Proteolytic Stability,Biotechnology Advances, 2022, 59, 107962.

(5) Zhenheng Lai, Hongyu Chen, Xiaojie Yuan, Jiahui Tian, Na Dong, Xingjun Feng, Anshan Shan*. Designing Double-Site Lipidated Peptide Amphiphiles as a Potent Antimicrobial Biomaterial to Combat Multidrug-Resistant Bacteria, Frontiers in Microbiology, 2022, 13:1074359.

(6) Zhenheng Lai, Qiao Jian, Guoyu Li, Changxuan Shao, Yongjie Zhu, Xiaojie Yuan, Hongyu Chen, Anshan Shan*.Self-Assembling Peptide Dendron Nanoparticles with High Stability and a Multimodal Antimicrobial Mechanism of Action, ACS Nano, 2021, 15 (10),15824-15840.

(7) Peng Tan#, Zhenheng Lai#, Yongjie Zhu, Changxuan Shao, Muhammad Usman Akhtar, Weifen Li, Xin Zheng, Anshan Shan*. Multiple Strategy Optimization of Specifically Targeted Antimicrobial Peptide Based on Structure-Activity Relationships to Enhance Bactericidal Efficiency, ACS Biomaterials Science & Engineering. 2020, 6(1), 398-414.

(8) Zhenheng Lai#, Peng Tan#, Yongjie Zhu, Changxuan Shao,Anshan Shan*, Lu Li. Highly Stabilized α-Helical Coiled Coils Kill Gram-Negative Bacteria by Multicomplementary Mechanisms under Acidic Condition,ACS Applied Materials & Interfaces, 2019, 11(25), 22113-22128.