副教授
1987年生，南京大学化学化工学院副教授。2015年获南京大学理学博士学位，2016年留校担任副研究员，2020年任职副教授。获得国家自然科学基金青年基金、面上项目、江苏省自然科学基金优秀青年基金等项目支持。主要研究方向为光学显微成像技术、电分析化学和纳米生物传感等。欢迎对光学显微成像、纳米生物分析等方向感兴趣的同学加入我们的研究团队。
12/2020 – 至今：
南京大学，化学化工学院，副教授；
01/2016 – 12/2020：
南京大学，化学化工学院，副研究员
主要研究方向着眼于功能纳米材料的合成及其在单细胞、单分子成像分析中的应用研究，利用自主研制的时空分辨光谱显微镜、石墨烯电化学显微镜、表面等离子共振耦合暗场显微镜、电致化学发光显微镜等仪器设备及配套软件，发展出一系列基于单颗粒纳米探针技术的单分子、单细胞原位成像分析方法，并将其应用于解决单细胞完整自噬过程的动态追踪、细胞内局部瞬态热的时空分辨成像、单分子电子传递过程的动力学检测、miRNA单分子杂交动力学分析等一系列生命分析中的科学问题。目前以第一作者和通讯作者身份在Nat. Commun.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Nano Lett.、ACS Nano、Adv. Func. Mater.、Chem. Sci.、Anal. Chem. 等国际高水平期刊上发表论文16篇。主持国家自然科学基金青年科学基金、面上项目、江苏省自然科学基金优秀青年科学基金等项目。
1. Xueqin Chen, Qing Xia, Yue Cao, Qianhao Min, Jianrong Zhang, Zixuan Chen*, Hong-Yuan Chen, Jun-Jie Zhu*, Imaging the transient heat generation of individual nanostructures with a mechanoresponsive polymer, Nature Communications 8, 1498 (2017).
2. Qing Xia, Zixuan Chen (Co-first Author), Pengwei Xiao, Minxuan Wang, Xueqin Chen, Jian-Rong Zhang, Hong-Yuan Chen, Jun-Jie Zhu*, Fermi level-tuned optics of graphene for attocoulomb-scale quantification of electron transfer at single gold nanoparticles, Nature Communications 10, 3849 (2019).
3. Zixuan Chen, Jingjing Li, Xueqin Chen, Juntao Cao, Jianrong Zhang, Qianhao Min*, Jun-Jie Zhu*, Single Gold@ Silver Nanoprobes for Real-Time Tracing the Entire Autophagy Process at Single-Cell Level, Journal of the American Chemical Society 137 (5), 1903-1908 (2015).
4. Cheng Ma, Shaojun Wu, Yang Zhou, Hui-Fang Wei, Jianrong Zhang, Zixuan Chen*, Jun-Jie Zhu, Yuehe Lin*, Wenlei Zhu*, Bio-Coreactant-Enhanced Electrochemiluminescence Microscopy of Intracellular Structure and Transport, Angewandte Chemie, DOI: 10.1002/ange.202012171 (2020).
5. Zixuan Chen, Yujiao Peng, Yue Cao, Hui Wang, Jian-Rong Zhang, Hong-Yuan Chen, Jun-Jie Zhu*, Light-Driven Nano-oscillators for Label-Free Single-Molecule Monitoring of MicroRNA, Nano Letters 18 (6), 3759-3765 (2018).
6. Cheng Ma, Hui-Fang Wei, Min-Xuan Wang, Shaojun Wu, Yu-Chung Chang, Jianrong Zhang, Li-Ping Jiang, Wenlei Zhu*, Zixuan Chen*, Yuehe Lin*, Hydrogen Evolution Reaction Monitored by Electrochemiluminescence Blinking at Single-Nanoparticle Level, Nano Letters 20 (7), 5008-5016 (2020).
7. Zixuan Chen, Xiaonan Shan, Yan Guan, Shaopeng Wang, Jun-Jie Zhu*, Nongjian Tao*, Imaging Local Heating and Thermal Diffusion of Nanomaterials with Plasmonic Thermal Microscopy, ACS nano 9 (12), 11574–11581 (2015).
8. Lingling Li, Ziyi Zhang, Ying Chen, Qin Xu, Jian-Rong Zhang, Zixuan Chen*, Yun Chen*, Jun-Jie Zhu*, Sustainable and Self‐Enhanced Electrochemiluminescent Ternary Suprastructures Derived from CsPbBr3 Perovskite Quantum Dots, Advanced Functional Materials 29, 1902533 (2019).
9. Cheng Ma, Wanwan Wu, Lingling Li, Shaojun Wu, Jian-Rong Zhang, Zixuan Chen*, Jun-Jie Zhu*, Dynamically Imaging Collision Electrochemistry of Single Electrochemiluminescence Nano-Emitters, Chemical Science 9, 6167-6175 (2018).
10. Gen Liu, Baokang Jin, Cheng Ma, Zixuan Chen*, Jun-Jie Zhu, Potential-Resolved Electrochemiluminescence Nanoprobes for Visual Apoptosis Evaluation at Single-Cell Level, Analytical Chemistry 91 (9), 6363-6370 (2019).
11. Shaojun Wu, Cheng Ma, Yan Gao, Yu Su, Qing Xia, Zixuan Chen*, Jun-Jie Zhu*, Dynamic Detection of Endogenous Hydroxyl Radicals at Single-Cell Level with Individual Ag–Au Nanocages, Analytical chemistry 92 (14), 9940-9947 (2020).
12. Gen Liu, Cheng Ma, Baokang Jin*, Zixuan Chen*, Faliang Cheng, Jun-Jie Zhu, Electrochemiluminescence Investigation of Glucose Transporter 4 Expression at Skeletal Muscle Cells Surface Based on a Graphene Hydrogel Electrode, Analytical chemistry 91 (4), 3021–3026 (2019).
13. Ying Chen, Jiaju Fu, Chen Cui, Dechen Jiang*, Zixuan Chen*, Hong-Yuan Chen, Jun-Jie Zhu*, In situ Visualization of Electrocatalytic Reaction Activity at Quantum Dots for Water Oxidation, Analytical Chemistry 90 (14), 8635–8641 (2018).
14. Gen Liu, Cheng Ma, Baokang Jin*, Zixuan Chen*, Jun-Jie Zhu*, Direct electrochemiluminescence imaging of a single cell on a chitosan film modified electrode, Analytical Chemistry 90 (7), 4801-4806 (2018).
15. Cheng Ma, Wanwan Wu, Yujiao Peng, Min-Xuan Wang, Gang Chen, Zixuan Chen*, Jun-Jie Zhu*, A Spectral Shift-Based Electrochemiluminescence Sensor for Hydrogen Sulphide, Analytical Chemistry 90 (2), 1334-·339 (2017).
16. Yue Cao, Wenlei Zhu, Lingling Li, Ziyi Zhang, Zixuan Chen*, Yuehe Lin*, Jun-Jie Zhu*, Size-selected and surface-passivated CsPbBr3 perovskite nanocrystals for self-enhanced electrochemiluminescence in aqueous media, Nanoscale 12, 7321-7329 (2020).
南京市仙林大道163号化学楼 G325
E-mail:chenzixuan@nju.edu.cn
