教授 博士生导师
微小RNA调控机制，核酸药物靶向输送和治疗.
1969年生。1990，1993年于南京大学化学系分别获学士和硕士学位，1993年进入南京大学生物化学系工作。2003年于南京大学获生物化学与分子生物学博士学位，2004-2007年在美国弗吉尼亚大学从事博士后研究。现主持2项国家自然科学基金和1项江苏省自然科学基金项目，参与 “重大新药创制”、863、973等国家重大项目的研究。已发表SCI收录论文30多篇，授权2项中国发明专利，申请国际发明专利1项和中国发明专利5项。主讲细胞生物学，分子生物学进展和生物化学分析技术等课程。
1. Jiangning Chen, Huan Chen, Pei Li, Huajia Diao, Shiyu Zhu, Lei Dong, Rui Wang, Ting Guo, Jianning Zhao, Junfeng Zhang*, Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered integrated scaffolds, Biomaterials, 2011, 32, 4793-4805.
2. Xiaoyun Cheng, Fengbo Gao, Jiawei Xiang, Xiqun Jiang, Jiangning Chen*, Junfeng Zhang*, Galactosylated alpha,beta-poly (2-hydroxyethyl)-L-aspartamide -bound doxorubicin, improved antitumor activity against hepatocellular carcinoma with reduced hepatotoxicity, Anti-Cancer Drugs, 2011, 22, 136-147.
3. Dan Xu, Ke Wu, Qiuhong Zhang, Heyi Hu, Kai Xi, Qingming Chen, Xuehai Yu, Jiangning Chen*, Xudong Jia*, Synthesis and biocompatibility of anionic polyurethane nanoparticles coated with adsorbed chitosan, Polymer, 2010, 51, 1926-1933.
4. Lei Dong, Suhua Xia, Huan Chen, Jiangning Chen*，and Junfeng Zhang*, Spleen-specific suppression of TNF-α by cationic hydrogel-delivered antisense nucleotides for the prevention of arthritis in animal models, Biomaterials, 2009, 30(26), 4416-26.
5. Lei Dong, Suhua Xia, Yi Luo, Huajia Diao, Jianing Zhang, Jiangning Chen*, Junfeng Zhang*, Targeting delivery oligonucleotide into macrophages by cationic polysaccharide from Bletilla striata successfully inhibited the expression of TNF-alpha, Journal of Controlled Release, 2009, 134(3), 214-20.
jnchen@nju.edu.cn
