教授 博士生导师 硕士生导师
电子邮箱:
入职时间:2014-01-16
职务:化学系副主任
办公地点:辽宁省沈阳市和平区文化路3-11东北大学化学馆
杨婷,女,博士,东北大学教授,博士生导师,东北大学理学院化学系副主任。2004-2013年于东北大学分析科学研究中心分别获得本、硕、博学位,导师为王建华教授。2012.11-2013.11获得国家建设高水平高校公派奖学金,赴美国The University of Texas, Arlington大学作联合培养博士研究生。2014年起于东北大学理学院任讲师,2016年晋升为副教授,2019年破格晋升为教授。2020年获“兴辽英才计划”青年拔尖人才。主要从事分析化学与微生物学交叉学科的基础研究及应用研究。任职以来,主持国家自然科学基金委面上项目等国家及省部级项目7项,并在Nature Communications, ACS Nano, Analytical Chemistry, Environ. Sci. Technol等SCI期刊上发表论文六十余篇。
主要研究方向:
1.基于噬菌体的分离分析平台
2.硼酸亲和作用及免疫亲和分析
3.微生物分析及鉴定
承担项目
1) 国家自然科学基金面上项目《基于硼酸定向偶联免疫亲和的外泌体高效捕获与原位分析》,22174011,60万元,2022.1-2025.12;
2) 辽宁省“兴辽英才计划”青年拔尖人才项目《基于液体活检的重大疾病诊断分析》,XLYC2007102,50万元,2021.01-2023.12;
3) 国家自然科学基金面上项目《基于M13噬菌体的循环肿瘤细胞高效分离富集与分析新策略》,21874014,66万元,2019.1-2022.12;
4) 国家自然科学基金青年项目《金属蛋白-纳米复合物用于构建高选择性传感分析系统》,21405010,25万元,2015.1-2017.12;
5) 教育部基本科研业务费优秀青年人才培育项目《噬菌体自传感平台的构建与特定疾病标志物筛查》,N180505021,20万元,2019.1-2021.12;
6) 教育部基本科研业务费种子基金《噬菌体在生物传感分析中的应用研究》,N160504008,11万元,2017.1-2018.12;
7) 教育部基本科研业务费种子基金《基于金属蛋白的新型重金属传感分析研究》,N140504003,12万元,2015.1-2016.12;
代表性论文
1. Hui-Da Li, Yuan-Qiang Chen, Yan Li, Xing Wei, Si-Yi Wang, Ying Cao, Rui Wang, Cong Wang, Jing-Yue Li, Jian-Yi Li*, Hong-Ming Ding*, Ting Yang*, Jian-Hua Wang and Chuanbin Mao*. Harnessing virus flexibility to selectively capture and profile rare circulating target cells for precise cancer subtyping. Nature Communications. 2024, 15, 5849.
2. Na Wu, Ka-Ying Wong, Xin Yu, Jia-Wei Zhao, Xin-Yu Zhang, Jian-Hua Wang, and Ting Yang*. Multispectral 3D DNA Machine Combined with Multimodal Machine Learning for Noninvasive Precise Diagnosis of Bladder Cancer. Analytical chemistry 2024, 96, 24, 10046–10055
3. Xin Wang, Huida Li, Jianyu Yang, Chengxin Wu, Mingli Chen, Jianhua Wang, and Ting Yang*. Chemical Nose Strategy with Metabolic Labeling and “Antibiotic-Responsive Spectrum” Enables Accurate and Rapid Pathogen Identification. Analytical chemistry 2024, 96, 427−436
4. Meijun Liu, Xing Wei, Chengxin Wu, Jinhui Liu, Yujia Wei, Xuesheng Wang, Ming-Li Chen, Ting Yang,* and Jian-Hua Wang*. Single Cell Phenotypic Analysis for Cancer Stem Cell Identification by Dual-Isotope ICP-QMS. Anal. Chem. 2023, 95, 14447−14454
5. Ying Cao, Na Wu, Hui-Da Li, Jing-Wen Xue, Rui Wang, Ting Yang,* Jian-Hua Wang. Efficient Pathogen Capture and Sensing Promoted by Dynamic Deformable Nanointerfaces. Small. 2022, 18 (51), 2203962
6. Siyi Wang, Jiasen Cui, Qian Fan, Jiaxing Gan, Chunran Liu, Yuanhe Wang*, Ting Yang*, Jianhua Wang, and Chaoyong Yang. Reversible and Highly Ordered Biointerfaces for Efficient Capture and Nondestructive Release of Circulating Tumor Cells. Analytical chemistry 2022, 94, 26, 9450–9458
7. Na Wu, Xin-Yu Zhang, Jie Xia, Xin Li, Ting Yang*, and Jian-Hua Wang. Ratiometric 3D DNA Machine Combined with Machine Learning Algorithm for Ultrasensitive and High-Precision Screening of Early Urinary Diseases, ACS Nano 2021, 15(12), 19522–19534
8. Na Wu, Kun Wang, Yi-Ting Wang, Ming-Li Chen, Xu-Wei Chen, Ting Yang*, Jian-Hua Wang. Three-Dimensional DNA Nanomachine Biosensor by Integrating DNA Walker and Rolling Machine Cascade Amplification for Ultrasensitive Detection of Cancer-Related Gene. Analytical chemistry 2020, 92, 16, 11111–11118.
9. Yi-Ting Wang, Na Wu, Ting Yang*, Jian-Hua Wang*. Unusual Selective Response to Glycoprotein over Sugar Facilitates Ultrafast Universal Fluorescent Immunoassay of Biomarkers. Analytical chemistry 2020, 92, 7, 5540-5545.
10. Jian-Yu Yang, Xin-Di Jia, Xiao-Yan Wang, Meng-Xian Liu, Ming-Li Chen*, Ting Yang *, and Jian-Hua Wang. Discrimination of antibiotic-resistant Gram-negative bacteria with a novel 3D nano sensing array. Chemical Communications 2020, 56, 1717-1720.
[1]液体活检
候选人依托辽宁省流动分析与装备重点实验室组建了包括教授(1人)、及博士研究生7人在内的研究团队。近年来,该团队围绕面向液体活检的样品预处理理论与方法、亲和界面微纳组装与调控及生命分析等领域开展工作,在相关领域取得了一系列原创性科研成果。目前该团队已在ACS Nano, Small, Anal. Chem.等期刊上发表SCI论文60余篇,候选人第一或通讯作者论文40篇,SCI他引700余次。候选人于2020年获得辽宁省“兴辽英才”青年拔尖人才称号。实验室培养的博士分别就职于大连民族大学、苏州科技大学,从该团队毕业的硕士研究生在科研工作中也得到了广泛好评。