研究领域

p21，膀胱癌，RNA激活，良性前列腺增生症

论文成果

• Targeted p21WAF1/CIP1 Activation by miR-1236 Inhibits Cell Proliferation and Correlates with Favorable Survival in Renal Cell Carcinoma.
• Promoter-associated endogenous and exogenous small RNAs suppress human bladder cancer cells metastasis by activating p21CIP1/WAF1 expression.
• Overexpression of p53 activated by small activating RNA suppresses the growth of human prostate cancer cells.
• Targeted p53 activation by saRNA suppresses human bladder cancer cells growth and metastasis.
• 盖强强,胡佳,李凡,叶章群. The suppressive effects of miR-1180-5p on the proliferation and tumorigenicity of bladder cancer cells. .HISTOLOGY AND HISTOPATHOLOGY .2017 ,32 (1) :77-86

专利

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著作成果

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科研项目

• miRNA激活p21基因表达机制及在膀胱肿瘤靶向治疗作用研究
• 双层PLCL纳米纤维管结合脂肪源干细胞构建功能性尿道的可行性研究
• dsRNA 激活膀胱癌细胞p21 基因的RNAa 机制研究
• hnRNP家族蛋白及相关蛋白质参与小RNA激活前列腺癌细胞株p21基因表达的机制研究