Xuesong Wu   

Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates
Gender:Male Status:Employed Department:School of Chemistry and Chemical Engineering Education Level:Postgraduate (Doctoral) Degree:Doctoral Degree in Science Discipline:Organic Chemistry

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Language: 中文

Profile


华中科技大学化学与化工学院教授、博士生导师。于中国科学技术大学获得学士和博士学位,先后在美国IUPUI和加州大学欧文分校从事博士后研究。在J. Am. Chem. Soc.Nat. Commun.Angew. Chem. Int. Ed. ACS Catal. Chem. Sci. 等国际学术期刊上以通讯作者或第一作者发表论文30篇,论文被引用总计1800余次,多篇论文入选ESI高被引论文。


研究方向


目前课题组主要研究兴趣包括:

1)有机合成新方法新反应的研究,涉及自由基化学、光化学合成、及不对称催化

2)功能高分子新材料的合成与改性

    

课题组诚招有机化学博士后、博士研究生和推免硕士研究生,热忱欢迎有志于有机合成研究的青年才俊加盟。


代表性论文



29. Zhang, Qi; Wu, Shanghui; Wu, Xuesong* “Iron/photoredox dual-catalyzed redox-neutral double decarboxylative C(sp3)–C(sp3) cross-coupling.” Green Chem. 2024, 26, 11334-11339.

28. Guo, Hong-Mei;# Wang, Jia-Jin;# Xiong, Yanjiao; Wu, Xuesong* “Visible-Light-Driven Multicomponent Reactions for the Versatile Synthesis of Thioamides by Radical Thiocarbamoylation.” Angew. Chem. Int. Ed. 2024e202409605.

27. Xiong, Yanjiao; Zhang, Qi; Zhang, Jun; Wu, Xuesong* “Visible-Light-Driven Deoxygenative Heteroarylation of Alcohols with Heteroaryl Sulfones.” J. Org. Chem. 2024, 89, 3629-3634.

26. Xiong, Yanjiao; Wu, Xuesong* “Deoxygenative coupling of alcohols with aromatic nitriles enabled by direct visible light excitation.” Org. Biomol. Chem. 202321, 9316-9320.

25. He, Bin-Qing; Wu, Xuesong* “Deuterium- and Electron-Shuttling Catalysis for Deoxygenative Deuteration of Alcohols.” Org. Lett. 202325, 6571-6576.

24. Zhang, Xiaoyi;# Ning, Shen;# Li, YiXiong, Yanjiao; Wu, Xuesong* “Hydrogen Atom Transfer for C(sp3)–H Functionalization Enabled by Photoredox/Thianthrene/Methanol Synergistic Catalysis.” ChemCatChem, 2023e202300311.

23. Bao, Wen-Hui; Wu, Xuesong* “Visible-Light-Driven Photocatalyst-Free Deoxygenative Radical Transformation of Alcohols to Oxime Ethers.” J. Org. Chem. 202388, 3975-3980.

22. Zhang, Wei;# Ning, Shen;# Li, YiWu, Xuesong* “Visible-Light-Driven Photocatalyst-Free Deoxygenative Alkylation of Imines with Alcohols.” Chem. Commun. 202258, 12843-12846.

21. Wang, Xiaochuang; Li, Yi; Zhang, JunWu, Xuesong* “Organophotoredox-Catalyzed Ring-opening gem-Difluoroallylation of Nonstrained Cycloalkanols.” Mol. Catal. 2022, 533, 112788.

20. Xiong, Yanjiao; Zhang, Xiaoyi; Guo, Hong-MeiWu, Xuesong* “Photoredox/Persistent Radical Cation Dual Catalysis for Alkoxy Radical Generation from Alcohols.” Org. Chem. Front. 2022, 9, 3532-3539.

19. Guo, Hong-Mei#; He, Bin-Qing#Wu, Xuesong* “Direct Photoexcitation of Xanthate Anions for Deoxygenative Alkenylation of Alcohols.” Org. Lett. 2022, 24, 3199-3204.

18. Wang, Xiaochuang; Li, Yi; Wu, Xuesong* “Photoredox/Cobalt Dual Catalysis Enabled Regiospecific Synthesis of Distally Unsaturated Ketones with Hydrogen Evolution.” ACS Catal. 202212, 3710-3718.

17. Guo, Hong-MeiWu, Xuesong* “Selective Deoxygenative Alkylation of Alcohols via Photocatalytic Domino Radical Fragmentations.” Nat. Commun. 202112: 5365.

16. Wu, Xuesong#; Cruz, Faben A.#; Lu, Alexander; Dong, Vy M.* “Tandem Catalysis: Transforming Alcohols to Alkenes by an Oxidative Dehydroxymethylation.” J. Am. Chem. Soc. 2018140, 10126-11593.

15. Wu, X.; Riedel, J.; Dong, V. M.* “Transforming Olefins into γ,δ-Unsaturated Nitriles through Copper Catalysis.” Angew. Chem. Int. Ed. 2017, 56, 11589-11593.

14. Wu, X.; Chen, Z.; Bai, Y.; Dong, V. M.* “Diastereodivergent Construction of Bicyclic γ-Lactones via Enantioselective Ketone Hydroacylation.” J. Am. Chem. Soc. 2016, 138, 12013-12016.

13. Wu, X.; Miao, J.; Li, Y.; Li, G.*; Ge, H.* “Copper-Promoted Site-Selective Carbonylation of sp3 and sp2 C–H Bonds with Nitromethane.” Chem. Sci. 2016, 7, 5260-5264.

12. Wu, X.; Zhao, Y.; Ge, H.* “Pyridine-Enabled Copper-Promoted Cross Dehydrogenative Coupling of C(sp2)−H and Unactivated C(sp3)−H Bonds” Chem. Sci. 2015, 6, 5978-5983.

11. Wu, X.; Wang, M.; Zhang, G.; Zhao, Y.; Wang, J.*; Ge, H.* “Copper-Catalyzed Diastereoselective Aerobic Intramolecular Dehydrogenative Coupling of Hydrazones via sp3 C−H Functionalization.” Chem. Sci. 2015, 6, 5882-5890.

10. Wu, X.; Zhao, Y.; Ge, H.* “Direct Aerobic Carbonylation of C(sp2)−H and C(sp3)−H Bonds through Ni/Cu Synergistic Catalysis with DMF as the Carbonyl Source.” J. Am. Chem. Soc. 2015, 137, 4924-4927.

9. Wu, X.; Yang, K.; Zhao, Y.; Sun, H.; Li, G.*; Ge, H.* “Cobalt-Catalysed Site-Selective Intra- and Intermolecular Dehydrogenative Amination of Unactivated sp3 Carbons.” Nat. Commun. 2015, 6: 6442.

8. Wu, X.; Zhao, Y.; Ge, H.* “Copper-Promoted Site-Selective Acyloxylation of Unactivated C(sp3)–H Bonds.” Chem. Asian J. 2014, 9, 2736-2739.

7. Wu, X.; Zhao, Y.; Ge, H.* “Nickel-Catalyzed Site-Selective Amidation of Unactivated C(sp3)–H Bonds.” Chem. Eur. J. 2014, 20, 9530-9533.

6. Wu, X.; Zhang, G.; Zhao, Y.; Ge, H.* “Copper-Catalyzed Site-Selective Intramolecular Amidation of Unactivated C(sp3)–H Bonds.” Angew. Chem. Int. Ed. 2014, 53, 3706-3710.

5. Wu, X.; Zhao, Y.; Ge, H.* “Nickel-Catalyzed Site-Selective Alkylation of Unactivated C(sp3)–H Bonds.” J. Am. Chem. Soc. 2014, 136, 1789-1792.

4. Wu, X.; Zhou, M.-G.; Chen, Y.; Tian, S.-K.* “Catalytic Allylation of Hypophosphorous Acid and H-Phosphinic Acids with Primary Allylic Amines.” Asian J. Org. Chem. 2014, 3, 711-714.

3. Wu, X.; Chen, Y.; Li, M.-B.; Zhou, M.-G.; Tian, S.-K.* “Direct Substitution of Primary Allylic Amines with Sulfinate Salts.” J. Am. Chem. Soc. 2012, 134, 14694-14697.

2. Wu, X.; Tian, S.-K.* “Catalytic Asymmetric Cleavage of sp3 C–N Bonds for Access to Highly Enantioenriched N-Benzylic Sulfonamides.” Chem. Commun. 2012, 48, 898-900.

1. Shao, Y.-D.; Wu, X.; Tian, S.-K.* “Stereoselective Olefination and Regiospecific Vicinal Difunctionalization of Imines with α-(Benzothiazol-2-ylsulfonyl) Carbonyl Compounds.” Eur. J. Org. Chem. 2012, 1590-1596.







Educational Experience

  • 2002.9-2006.7  

    中国科学技术大学       化学       Undergraduate (Bachelor’s degree)       Bachelor's Degree in Science

  • 2006.9-2012.7  

    中国科学技术大学       有机化学       Postgraduate (Doctoral)       Doctoral Degree in Science