Jiang Gong   研究员(自然科学)

截止2024年8月24日,累计发表SCI论文153篇。其中第一作者/通讯作者85篇,包括国际一流期刊Progress in Polymer Science(影响因子26),Advanced Materials(影响因子27.4),Advanced Energy Materials (影响因子24.4),Angewandte Chemie International Edition(影响因子16.1),Chem(影响因子19.1),Applied Catalysis B: Environmental(影响因子20.2,4篇),Chemical Engineering Journal(影响因子13.3,11篇),Jour...Detials

Weak ion-exchange based magnetic swarm for targeted drug delivery and chemotherapy

Release time:2024-08-25  Hits:

  • Indexed by:Journal paper
  • First Author:Kai Feng,
  • Correspondence Author:Ran Niu
  • Co-author:Wenqi Shen,Ling Chen,Jiang Gong,Thomas Palberg,Jinping Qu
  • Journal:Small
  • Included Journals:SCI、EI
  • Discipline:Engineering
  • First-Level Discipline:Material Science and Engineering
  • Document Type:J
  • Volume:20
  • Page Number:2306798
  • Date of Publication:2024-05-02
  • Abstract:Swimming microrobots that are actuated by multiple stimuli/fields display various intriguing collective behaviors, ranging from phase separation to clustering and giant number fluctuation; however, it is still chanllenging to achieve multiple responses and functionalities within one colloidal system to emulate high environmental adaptability and improved tasking capability of natural swarms. In this work, a weak ion-exchange based swarm is presented that can self-organize and reconfigure by chemical, light, and magnetic fields, showing living crystal, amorphous glass, liquid, chain, and wheel-like structures. By changing the frequency and strength of the rotating magnetic field, various well-controlled and fast transformations are obtained. Experiments show the high adaptability and functionality of the microrobot swarm in delivering drugs in confined spaces, such as narrow channels with turns or obstacles. The drug-carrying swarm exhibits excellent chemtherapy for Hela and CT26 cells due to the pH-enhanced drug release and locomotion. This reconfigurable microswarm provides a new platform for biomedical and environmental applications.
  • Links to published journals:https://doi.org/10.1002/smll.202306798